• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
(De-) oiling inflammasomes.（去）脂化炎症小体。
Immunity. 2013 Jun 27;38(6):1088-90. doi: 10.1016/j.immuni.2013.06.006.
2
Omega-3 fatty acids prevent inflammation and metabolic disorder through inhibition of NLRP3 inflammasome activation.ω-3 脂肪酸通过抑制 NLRP3 炎性小体的激活来预防炎症和代谢紊乱。
Immunity. 2013 Jun 27;38(6):1154-63. doi: 10.1016/j.immuni.2013.05.015.
3
Caspase-1 autoproteolysis is differentially required for NLRP1b and NLRP3 inflammasome function.半胱天冬酶-1自身催化对NLRP1b和NLRP3炎性小体功能的需求存在差异。
Proc Natl Acad Sci U S A. 2014 Dec 2;111(48):17254-9. doi: 10.1073/pnas.1415756111. Epub 2014 Nov 17.
4
Hyperuricemia-induced NLRP3 activation of macrophages contributes to the progression of diabetic nephropathy.高尿酸血症诱导的巨噬细胞NLRP3激活促进糖尿病肾病的进展。
Am J Physiol Renal Physiol. 2015 May 1;308(9):F993-F1003. doi: 10.1152/ajprenal.00637.2014. Epub 2015 Jan 28.
5
K⁺ drops tilt the NLRP3 inflammasome.钾离子下降会使 NLRP3 炎症小体发生倾斜。
Immunity. 2013 Jun 27;38(6):1085-8. doi: 10.1016/j.immuni.2013.06.001.
6
Frontline Science: Specialized proresolving lipid mediators inhibit the priming and activation of the macrophage NLRP3 inflammasome.前沿科学：特异性促解决脂质介质抑制巨噬细胞 NLRP3 炎性体的启动和激活。
J Leukoc Biol. 2019 Jan;105(1):25-36. doi: 10.1002/JLB.3HI0517-206RR. Epub 2018 Mar 30.
7
Regulation and Function of the Nucleotide Binding Domain Leucine-Rich Repeat-Containing Receptor, Pyrin Domain-Containing-3 Inflammasome in Lung Disease.含核苷酸结合结构域富含亮氨酸重复序列受体、含吡啉结构域的3炎性小体在肺部疾病中的调控与功能
Am J Respir Cell Mol Biol. 2016 Feb;54(2):151-60. doi: 10.1165/rcmb.2015-0231TR.
8
Unsaturated fatty acids prevent activation of NLRP3 inflammasome in human monocytes/macrophages.不饱和脂肪酸可防止人单核细胞/巨噬细胞中 NLRP3 炎性小体的激活。
J Lipid Res. 2013 Nov;54(11):2998-3008. doi: 10.1194/jlr.M037861. Epub 2013 Sep 3.
9
Fatty acid synthesis and NLRP3-inflammasome.脂肪酸合成与NLRP3炎性小体
Oncotarget. 2015 Sep 8;6(26):21765-6. doi: 10.18632/oncotarget.4781.
10
Targeting the TXNIP-NLRP3 interaction with PSSM1443 to suppress inflammation in sepsis-induced myocardial dysfunction.靶向 TXNIP-NLRP3 相互作用用 PSSM1443 抑制脓毒症诱导的心肌功能障碍中的炎症反应。
J Cell Physiol. 2021 Jun;236(6):4625-4639. doi: 10.1002/jcp.30186. Epub 2021 Jan 16.

引用本文的文献

1
Fundamentals of Membrane Lipid Replacement: A Natural Medicine Approach to Repairing Cellular Membranes and Reducing Fatigue, Pain, and Other Symptoms While Restoring Function in Chronic Illnesses and Aging.膜脂质置换基础：一种通过自然医学方法修复细胞膜、减轻疲劳、疼痛及其他症状，同时恢复慢性病和衰老状态下机体功能的方法。
Membranes (Basel). 2021 Nov 29;11(12):944. doi: 10.3390/membranes11120944.
2
Activation of NLRP3 Inflammasome by Palmitic Acid in Human Sebocytes.棕榈酸对人皮脂腺细胞中NLRP3炎性小体的激活作用
Ann Dermatol. 2021 Dec;33(6):541-548. doi: 10.5021/ad.2021.33.6.541. Epub 2021 Nov 4.
3
Dietary Fat, Sugar Consumption, and Cardiorespiratory Fitness in Patients With Heart Failure With Preserved Ejection Fraction.射血分数保留的心力衰竭患者的膳食脂肪、糖摄入量与心肺适能
JACC Basic Transl Sci. 2017 Oct 30;2(5):513-525. doi: 10.1016/j.jacbts.2017.06.009. eCollection 2017 Oct.
4
Inflammasomes, the eye and anti-inflammasome therapy.炎症小体，眼睛与抗炎症小体治疗。
Eye (Lond). 2018 Mar;32(3):491-505. doi: 10.1038/eye.2017.241. Epub 2017 Nov 24.

本文引用的文献

1
Omega-3 fatty acids prevent inflammation and metabolic disorder through inhibition of NLRP3 inflammasome activation.ω-3 脂肪酸通过抑制 NLRP3 炎性小体的激活来预防炎症和代谢紊乱。
Immunity. 2013 Jun 27;38(6):1154-63. doi: 10.1016/j.immuni.2013.05.015.
2
Inflammasomes and host defenses against bacterial infections.炎性小体与宿主防御细菌感染
Curr Opin Microbiol. 2013 Feb;16(1):23-31. doi: 10.1016/j.mib.2012.11.008. Epub 2013 Jan 11.
3
Association between omega-3 fatty acid supplementation and risk of major cardiovascular disease events: a systematic review and meta-analysis.ω-3 脂肪酸补充剂与主要心血管疾病事件风险的关联：系统评价和荟萃分析。
JAMA. 2012 Sep 12;308(10):1024-33. doi: 10.1001/2012.jama.11374.
4
Inflammation and lipid signaling in the etiology of insulin resistance.炎症和脂质信号在胰岛素抵抗的发病机制中的作用。
Cell Metab. 2012 May 2;15(5):635-45. doi: 10.1016/j.cmet.2012.04.001.
5
Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity.炎症小体介导的微生态失调调控非酒精性脂肪性肝病和肥胖的进展。
Nature. 2012 Feb 1;482(7384):179-85. doi: 10.1038/nature10809.
6
The inflammasome NLRs in immunity, inflammation, and associated diseases.炎性体 NLR 家族在免疫、炎症及相关疾病中的作用
Annu Rev Immunol. 2011;29:707-35. doi: 10.1146/annurev-immunol-031210-101405.
7
The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance.NLRP3 炎性体引发肥胖引起的炎症和胰岛素抵抗。
Nat Med. 2011 Feb;17(2):179-88. doi: 10.1038/nm.2279. Epub 2011 Jan 9.
8
GPR120 is an omega-3 fatty acid receptor mediating potent anti-inflammatory and insulin-sensitizing effects.GPR120 是一种 omega-3 脂肪酸受体，具有强大的抗炎和胰岛素增敏作用。
Cell. 2010 Sep 3;142(5):687-98. doi: 10.1016/j.cell.2010.07.041.
9
NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals.NLRP3 炎性小体对于动脉粥样硬化的形成是必需的，并且可以被胆固醇晶体激活。
Nature. 2010 Apr 29;464(7293):1357-61. doi: 10.1038/nature08938.
10
(n-3) Fatty acids and infectious disease resistance.(n-3)脂肪酸与抗感染能力
J Nutr. 2002 Dec;132(12):3566-76. doi: 10.1093/jn/132.12.3566.

（去）脂化炎症小体。

(De-) oiling inflammasomes.

机构信息

Division of Infectious Diseases and Immunology, Program in Innate Immunity, Department of Medicine, UMass Medical School, Worcester, MA 01605, USA.

出版信息

Immunity. 2013 Jun 27;38(6):1088-90. doi: 10.1016/j.immuni.2013.06.006.

DOI:10.1016/j.immuni.2013.06.006
PMID:23809158
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4397969/
Abstract

Activation of inflammasome signaling can produce harmful inflammation. In this issue of Immunity, Yan et al. (2013) suggest that omega-3 fatty acids commonly found in marine oils can suppress activation of NLRP3 and NLRP1b inflammasomes.

摘要

炎性体信号的激活可导致有害的炎症。在本期《免疫》中，Yan 等人（2013）提出，海洋油中常见的ω-3 脂肪酸可以抑制 NLRP3 和 NLRP1b 炎性体的激活。