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非裔美国成年人中重度抑郁症和双重抑郁症的残疾和合并症。

Disability and comorbidity among major depressive disorder and double depression in African-American adults.

机构信息

School of Nursing, University of Wisconsin, 600 Highland Ave, Clinical Science Center K6/326, Madison, WI 53792-2455, United States.

出版信息

J Affect Disord. 2013 Sep 25;150(3):1230-3. doi: 10.1016/j.jad.2013.05.089. Epub 2013 Jun 25.

Abstract

BACKGROUND

Few studies have examined differences in disability and comorbity among major depressive disorder (MDD), dysthymia, and double depression in African-Americans (AA).

METHODS

A secondary analysis was performed on AA in the National Survey of American Life. Interviews occurred 2001-2003. A four stage national area probability sampling was performed. DSM-IV-TR diagnoses were obtained with a modified version of the World Health Organization's expanded version of the Composite International Diagnostic Interview. Disability was measured by interview with the World Health Organization's Disability Assessment Schedule II.

RESULTS

Compared to non-depressed AA, AA endorsing MDD (t=19.0, p=0.0001) and double depression (t=18.7, p=0.0001) reported more global disability; AA endorsing MDD (t=8.5, p=0.0063) reported more disability in the getting around domain; AA endorsing MDD (t=19.1, p=0.0001) and double depression (t=12.1, p=0.0014) reported more disability in the life activities domain. AA who endorsed double depression reported similar disability and comorbidities with AA who endorsed MDD. Few AA endorsed dysthymia.

LIMITATIONS

This was a cross-sectional study subject to recall bias. The NSAL did not measure minor depression.

CONCLUSIONS

The current study supports the idea of deleting distinct chronic subtypes of depression and consolidating them into a single category termed chronic depression.

摘要

背景

很少有研究探讨非裔美国人(AA)中重度抑郁症(MDD)、心境恶劣障碍和双重抑郁之间在残疾和共病方面的差异。

方法

对国家生活调查中的 AA 进行了二次分析。访谈于 2001-2003 年进行。采用四阶段全国区域概率抽样法进行。DSM-IV-TR 诊断采用世界卫生组织扩大版综合国际诊断访谈的修改版获得。残疾通过世界卫生组织残疾评估表 II 进行访谈进行测量。

结果

与非抑郁 AA 相比,MDD(t=19.0,p=0.0001)和双重抑郁(t=18.7,p=0.0001)的 AA 报告了更多的总体残疾;MDD(t=8.5,p=0.0063)的 AA 报告了更多的行动障碍残疾;MDD(t=19.1,p=0.0001)和双重抑郁(t=12.1,p=0.0014)的 AA 报告了更多的生活活动障碍残疾。双相抑郁的 AA 报告的残疾和共病与单相抑郁的 AA 相似。很少有 AA 报告心境恶劣障碍。

局限性

这是一项横断面研究,存在回忆偏倚。NSAL 未测量轻度抑郁。

结论

目前的研究支持删除明确的慢性抑郁亚型并将其合并为一个称为慢性抑郁的单一类别。

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