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母亲受教育水平与低出生体重:一项荟萃分析。

Maternal education level and low birth weight: a meta-analysis.

机构信息

Programa de Pós-graduação em Saúde da Criança e do Adolescente, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.

出版信息

J Pediatr (Rio J). 2013 Jul-Aug;89(4):339-45. doi: 10.1016/j.jped.2013.01.003. Epub 2013 Jun 26.

Abstract

OBJECTIVE

To assess the association between maternal education level and birth weight, considering the circumstances in which the excess use of technology in healthcare, as well as the scarcity of these resources, may result in similar outcomes.

METHODS

A meta-analysis of cohort and cross-sectional studies was performed; the studies were selected by systematic review in the MEDLINE database using the following Key**words socioeconomic factors, infant, low birth weight, cohort studies, cross-sectional studies. The summary measures of effect were obtained by random effect model, and its results were obtained through forest plot graphs. The publication bias was assessed by Egger's test, and the Newcastle-Ottawa scale was used to assess study quality.

RESULTS

The initial search found 729 articles. Of these, 594 were excluded after reading the title and abstract; 21, after consensus meetings among the three reviewers; 102, after reading the full text; and three for not having the proper outcome. Of the nine final articles, 88.8% had quality ≥ six stars (Newcastle-Ottawa Scale), showing good quality studies. The heterogeneity of the articles was considered moderate. High maternal education showed a 33% protective effect against low birth weight, whereas medium degree of education showed no significant protection when compared to low maternal education.

CONCLUSIONS

The hypothesis of similarity between the extreme degrees of social distribution, translated by maternal education level in relation to the proportion of low birth weight, was not confirmed.

摘要

目的

评估母亲教育水平与出生体重之间的关系,同时考虑医疗保健中过度使用技术以及这些资源稀缺可能导致类似结果的情况。

方法

采用系统评价方法对队列研究和横断面研究进行荟萃分析,在 MEDLINE 数据库中使用以下关键词进行检索:社会经济因素、婴儿、低出生体重、队列研究、横断面研究。采用随机效应模型获取效应综合指标,并通过森林图显示结果。采用 Egger 检验评估发表偏倚,使用 Newcastle-Ottawa 量表评估研究质量。

结果

最初搜索发现了 729 篇文章。其中,594 篇在阅读标题和摘要后被排除;21 篇在三位审稿人达成共识后被排除;102 篇在阅读全文后被排除;还有三篇是因为没有适当的结局。在最终纳入的 9 篇文章中,88.8%(Newcastle-Ottawa 量表)的研究质量≥6 颗星,显示出高质量的研究。文章的异质性被认为是中度的。母亲的高教育水平对低出生体重有 33%的保护作用,而与低教育水平相比,中等程度的教育水平并没有显著的保护作用。

结论

母亲教育水平与低出生体重比例之间的社会分配极端程度相似的假设没有得到证实。

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