Han Gang, Schell Michael J, Kim Jongphil
Department of Biostatistics, H. Lee Moffitt Cancer Center & Research Institute, 12902 Magnolia Drive, Tampa, FL, 33612.
Stat Biopharm Res. 2012 Oct 1;4(4):348-356. doi: 10.1080/19466315.2012.698945.
The exact two-sided likelihood ratio test for testing the equality of two exponential means is proposed and proved to be the uniformly most powerful unbiased test. This exact test has advantages over two alternative approaches in that it is unbiased and more powerful while maintaining the type I error. The use of the proposed test is demonstrated in a non-small cell lung cancer clinical trial design.
提出了用于检验两个指数均值相等性的精确双边似然比检验,并证明其为一致最强大无偏检验。与两种替代方法相比,这种精确检验具有优势,因为它在保持I型错误的同时是无偏的且更具功效。在一项非小细胞肺癌临床试验设计中展示了所提出检验的应用。