Akiba J, Arzabe C W, Trempe C L
Eye Research Institute, Harvard Medical School, Boston, MA.
Ophthalmology. 1990 Jul;97(7):889-91. doi: 10.1016/s0161-6420(90)32486-7.
The authors evaluated the effect of posterior vitreous detachment (PVD) in 172 eyes (114 patients) with nonproliferative diabetic retinopathy on the development of retinal or optic disc neovascularization. Patients were followed for more than 6 months after the initial vitreous examination (mean, 32 months). None of the patients 39 years of age or younger had PVD, but this condition became more prevalent thereafter with age. In 124 eyes of patients 40 years of age or older, neovascularization developed eventually in 20 (22%) of 93 eyes without PVD but in only 1 (3%) of 29 eyes with complete PVD (P less than 0.05). A vitreous examination was invaluable in predicting the development of retinal or optic disc neovascularization in diabetic patients 40 years of age or older.
作者评估了172只眼（114例患者）非增殖性糖尿病视网膜病变患者中玻璃体后脱离（PVD）对视网膜或视盘新生血管形成的影响。在初次玻璃体检查后对患者进行了超过6个月的随访（平均32个月）。39岁及以下的患者均无PVD，但此后这种情况随年龄增长而更为普遍。在40岁及以上患者的124只眼中，93只无PVD的眼中最终有20只（22%）出现新生血管形成，而29只完全性PVD的眼中仅有1只（3%）出现新生血管形成（P<0.05）。玻璃体检查对于预测40岁及以上糖尿病患者视网膜或视盘新生血管形成非常重要。
