Tagawa H, McMeel J W, Furukawa H, Quiroz H, Murakami K, Takahashi M, Trempe C L
Ophthalmology. 1986 May;93(5):596-601. doi: 10.1016/s0161-6420(86)33690-x.
The vitreoretinal relationships in 1021 eyes of 570 patients with diabetic retinopathy and in 857 normal eyes were studied retrospectively in an attempt to identify the vitreous changes specifically related to diabetes. Complete posterior vitreous detachment (PVD) occurred in diabetic patients largely as part of the aging process, but proliferation interfered with its development. Complete PVD with nonproliferative diabetic retinopathy in the younger age groups was more prevalent in eyes treated by panretinal photocoagulation (PRP) than in untreated eyes and thus might have an association with PRP treatment. Partial PVD, seen mainly in proliferative diabetic retinopathy, had no correlation with aging. In the eyes of patients who were younger when diabetes was diagnosed, the development of partial PVD had a close correlation with the duration of diabetes. The data suggest the need for a clinical trial of early photocoagulation, before partial PVD develops, in younger-onset diabetic patients showing early proliferative changes.
对570例糖尿病视网膜病变患者的1021只眼和857只正常眼的玻璃体视网膜关系进行了回顾性研究，以试图确定与糖尿病特异性相关的玻璃体变化。完全性玻璃体后脱离（PVD）在糖尿病患者中很大程度上是衰老过程的一部分，但增殖会干扰其发展。在较年轻年龄组中，接受全视网膜光凝（PRP）治疗的眼中，伴有非增殖性糖尿病视网膜病变的完全性PVD比未治疗的眼更普遍，因此可能与PRP治疗有关。部分性PVD主要见于增殖性糖尿病视网膜病变，与衰老无关。在糖尿病诊断时较年轻的患者眼中，部分性PVD的发生与糖尿病病程密切相关。数据表明，对于表现出早期增殖性变化的年轻发病糖尿病患者，需要在部分性PVD发生之前进行早期光凝的临床试验。
