Al-Zaaidi Sultan, Al-Rashaed Saba, Al-Harthi Essam, Al-Kahtani Eman, Abu El-Asrar Ahmed M
Prince Sultan Medical Military City, Riyadh, Saudi Arabia.
Clin Ophthalmol. 2013;7:1001-14. doi: 10.2147/OPTH.S40056. Epub 2013 Jun 17.
To study the anatomical and visual outcomes and prognostic factors that may predict the outcomes of rhegmatogenous retinal detachment (RRD) in children.
A retrospective chart review was performed for patients 16 years of age or younger who underwent retinal reattachment surgery for RRD at the King Abdulaziz University Hospital from 1996 to 2005 and the King Khalid Eye Specialist Hospital from 2002 to 2006, Riyadh, Saudi Arabia. Good visual outcome was defined as ≥20/200. The association between two categorical variables was evaluated with the Chi-squared test or the exact test, as appropriate. Predictors for RRD and good final visual acuity were identified by conducting stepwise logistic regression analysis. P < 0.05 was statistically significant.
The study population comprised 148 patients (166 eyes). There were 104 (70%) males and 44 (30%) females. Mean age at presentation was 8.33 ± 3.26 years (range 1.5-16 years). The retina was reattached after one surgical procedure in 106 (63.8%) eyes and reattached in 130 (78.3%) eyes after multiple surgeries. Factors predicting recurrence after the first surgery were myopia (P = 0.028), proliferative vitreoretinopathy (PVR) at presentation (P = 0.024), and total retinal detachment (P = 0.032). Good final visual outcome was achieved in 60 (44.4%) eyes. Predictors of good visual acuity were: good visual acuity at presentation (P < 0.001); absence of PVR at presentation (P < 0.001); one quadrant of retinal detachment (P = 0.0024); macula on (P = 0.0107); absence of primary repair of a ruptured globe (P = 0.0059); no pars plana vitrectomy (PPV) (P = 0.0123); clear phakic lens at follow-up (P < 0.001); absence of postoperative complications (P < 0.001); absence of recurrence of RRD (P < 0.001); and absence of epiretinal membrane (P = 0.0088). Logistic regression analysis indicated that recurrence of RRD was associated with myopia and previous congenital cataract surgery; good final visual outcome was associated with macula on detachment and poor visual outcome was associated with recurrence of RRD and occurrence of postoperative complications and previous repair of a ruptured globe.
RRD in children is usually associated with a predisposing factor, a high rate of PVR, and total retinal detachment. Despite late diagnosis and the presence of PVR, favorable anatomical and visual outcomes can be achieved.
研究可预测儿童孔源性视网膜脱离(RRD)预后的解剖学和视觉预后及预后因素。
对1996年至2005年在阿卜杜勒阿齐兹国王大学医院以及2002年至2006年在沙特阿拉伯利雅得的哈立德国王眼科专科医院接受RRD视网膜复位手术的16岁及以下患者进行回顾性病历审查。良好的视觉预后定义为视力≥20/200。根据情况,使用卡方检验或确切检验评估两个分类变量之间的关联。通过逐步逻辑回归分析确定RRD和良好最终视力的预测因素。P<0.05具有统计学意义。
研究人群包括148例患者(166只眼)。男性104例(70%),女性44例(30%)。就诊时的平均年龄为8.33±3.26岁(范围1.5 - 16岁)。106只眼(63.8%)在一次手术后视网膜复位,130只眼(78.3%)在多次手术后视网膜复位。首次手术后预测复发的因素为近视(P = 0.028)、就诊时增殖性玻璃体视网膜病变(PVR)(P = 0.024)和全视网膜脱离(P = 0.032)。60只眼(44.4%)获得了良好的最终视觉预后。良好视力的预测因素为:就诊时视力良好(P < 0.001);就诊时无PVR(P < 0.001);视网膜脱离一个象限(P = 0.0024);黄斑在位(P = 0.0107);无眼球破裂一期修复(P = 0.0059);未行玻璃体切割术(PPV)(P = 0.0123);随访时晶状体透明(P < 0.001);无术后并发症(P < 0.001);无RRD复发(P < 0.001);无视网膜前膜(P = 0.0088)。逻辑回归分析表明,RRD复发与近视和既往先天性白内障手术有关;良好的最终视觉预后与黄斑在位脱离有关,不良视觉预后与RRD复发、术后并发症的发生以及既往眼球破裂修复有关。
儿童RRD通常与易感因素、高PVR发生率和全视网膜脱离有关。尽管诊断较晚且存在PVR,但仍可实现良好的解剖学和视觉预后。