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综述用于调查主要工业区周围空气污染对健康影响的流行病学方法。

A review of the epidemiological methods used to investigate the health impacts of air pollution around major industrial areas.

机构信息

French Institute for Public Health Surveillance, 12 Rue du Val d'Osne, 94415 Staint-Maurice, France.

出版信息

J Environ Public Health. 2013;2013:737926. doi: 10.1155/2013/737926. Epub 2013 Jun 2.

Abstract

We performed a literature review to investigate how epidemiological studies have been used to assess the health consequences of living in the vicinity of industries. 77 papers on the chronic effects of air pollution around major industrial areas were reviewed. Major health themes were cancers (27 studies), morbidity (25 studies), mortality (7 studies), and birth outcome (7 studies). Only 3 studies investigated mental health. While studies were available from many different countries, a majority of papers came from the United Kingdom, Italy, and Spain. Several studies were motivated by concerns from the population or by previous observations of an overincidence of cases. Geographical ecological designs were largely used for studying cancer and mortality, including statistical designs to quantify a relationship between health indicators and exposure. Morbidity was frequently investigated through cross-sectional surveys on the respiratory health of children. Few multicenter studies were performed. In a majority of papers, exposed areas were defined based on the distance to the industry and were located from <2 km to >20 km from the plants. Improving the exposure assessment would be an asset to future studies. Criteria to include industries in multicenter studies should be defined.

摘要

我们进行了文献回顾,以调查流行病学研究如何用于评估居住在工业附近对健康的影响。对主要工业区域周围空气污染的慢性影响进行了 77 篇论文的回顾。主要健康主题包括癌症(27 项研究)、发病率(25 项研究)、死亡率(7 项研究)和出生结果(7 项研究)。只有 3 项研究调查了心理健康。虽然来自许多不同国家的研究可用,但大多数论文来自英国、意大利和西班牙。一些研究是由公众关注或以前观察到的病例过多引起的。地理生态设计主要用于研究癌症和死亡率,包括用于量化健康指标与暴露之间关系的统计设计。发病率经常通过对儿童呼吸健康的横断面调查进行研究。进行了很少的多中心研究。在大多数论文中,暴露区域是根据与工业的距离来定义的,位于工厂 2 公里以内到 20 公里以外的地方。改进暴露评估将是未来研究的优势。应定义在多中心研究中纳入工业的标准。

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