Duodecim. 2013;129(11):1198-9.
The updated guideline on the treatment of dyslipidaemias is in concordance with European guidelines on cardiovascular disease prevention. Treatment of dyslipidaemia aims to reduce the risk of atherosclerotic vascular diseases. Therapeutic targets for LDL cholesterol, determined by risk assessment, range from concentration < 1.8 mmol/l (very high risk), < 2.5 mmol/l (high risk) to < 3.0 mmol/l (moderate or low risk). Lifestyle (diet, including replacement of saturated with unsaturated fat, physical activity, nonsmoking, stress management) is the cornerstone of treatment. Drug therapy, mainly statins, is considered when risk-stratified LDL targets are not reached otherwise.
血脂异常治疗的更新指南与欧洲心血管疾病预防指南一致。血脂异常治疗旨在降低动脉粥样硬化性血管疾病的风险。根据风险评估确定的低密度脂蛋白胆固醇治疗目标范围为浓度<1.8 mmol/L(极高风险)、<2.5 mmol/L(高风险)至<3.0 mmol/L(中低风险)。生活方式(饮食,包括用不饱和脂肪替代饱和脂肪、体育活动、戒烟、压力管理)是治疗的基石。当通过其他方式未达到风险分层的低密度脂蛋白目标时,考虑药物治疗,主要是他汀类药物。