S Afr Med J. 2012 Feb 23;102(3 Pt 2):178-87. doi: 10.7196/samj.5502.
The European Society of Cardiology together with the European Atherosclerosis Society published updated dyslipidaemia guidelines in 2011. SA Heart and the Lipid and Atherosclerosis Society of Southern Africa officially adopt these guidelines. This statement adapts aspects of the guidelines to the South African situation. Using the updated Framingham risk charts, interventional strategies are based according to the cardiovascular risk score and low-density lipoprotein cholesterol (LDL-C) levels. The Framingham risk score refers to the 10-year risk of any cardiovascular event, and includes four categories of risk. Treatment targets are those of the European guidelines. The LDL-C goal is 1.8 mmol/l for the very high-risk group (>30%), 2.5 mmol/l for the high-risk group (15-30%), and 3 mmol/l for those below 15% risk. Intensive management of dyslipidaemia in South Africa will significantly reduce the cardiovascular disease health burden.
欧洲心脏病学会与欧洲动脉粥样硬化学会于 2011 年发布了更新的血脂异常指南。南非心脏协会和南非脂质与动脉粥样硬化学会正式采用了这些指南。本声明根据南非的具体情况对指南的部分内容进行了调整。使用更新的弗雷明汉风险图表，根据心血管风险评分和低密度脂蛋白胆固醇（LDL-C）水平制定干预策略。弗雷明汉风险评分指的是任何心血管事件的 10 年风险，包括四个风险类别。治疗目标与欧洲指南相同。对于极高危组（>30%），LDL-C 目标为 1.8mmol/L；高危组（15%-30%）为 2.5mmol/L；低危组（<15%）为 3mmol/L。在南非加强血脂异常的管理将显著降低心血管疾病的健康负担。
