Department of Pharmacognosy, Faculty of Pharmacy, Ege University, 35100 Bornova, Izmir, Turkey.
Z Naturforsch C J Biosci. 2013 Mar-Apr;68(3-4):118-24.
GC-MS (gas chromatography-mass spectrometry) analyses of alkaloids in the aerial parts and bulbs of Galanthus rizehensis Stern (Amaryllidaceae), collected during two different vegetation periods, was performed. Twenty three alkaloids were identified in four different alkaloid extracts. Acetylcholinesterase (AChE) inhibitory activities of the alkaloid extracts were tested. Both the highest alkaloid diversity and the most potent inhibitory activity (IC50 12.94 microg/ml) were obtained in extracts from the bulbs of G. rizehensis collected during the fruiting period.
采用 GC-MS（气相色谱-质谱联用）方法对不同生育期的瑞香狼毒（Galanthus rizehensis Stern）地上部分和鳞茎中的生物碱进行了分析。从四个不同的生物碱提取物中鉴定出了 23 种生物碱。对生物碱提取物的乙酰胆碱酯酶（AChE）抑制活性进行了测试。在瑞香狼毒鳞茎的提取物中，获得了最高的生物碱多样性和最强的抑制活性（IC50 为 12.94μg/ml）。
