Kang-Lee Y A, Harper A E
Proc Soc Exp Biol Med. 1975 Jul;149(3):610=4. doi: 10.3181/00379727-149-38862.
Postnatal development of liver tyrosine aminotransferase and glucose-6-phosphatase, expressed as activity per gram of liver, occurred as rapidly in pups from pregnant rats fed throughout gestation a diet containing only 4% of casein as in pups from those fed the control diet containing 18% of casein supplemented with 0.3% of L-methionine. Total enzyme activity per liver was lower in pups from protein-restricted dams due to their smaller liver size. Dams fed the 4% casein diet during pregnancy gained much less weight than those fed the control diet and produced pups that weighed significantly less than control pups. Reproductive performance of a few dams fed 6% casein diets with or without amino acid supplements during gestation was comparable to that of dams fed the control diet. Litter size was not significantly reduced by the low-protein intake.
以每克肝脏的活性表示，肝脏酪氨酸转氨酶和葡萄糖-6-磷酸酶的产后发育情况，在整个妊娠期喂食仅含4%酪蛋白饮食的怀孕大鼠所产幼崽中，与喂食含18%酪蛋白并补充0.3%L-蛋氨酸的对照饮食的大鼠所产幼崽一样迅速。由于肝脏较小，蛋白质限制母鼠所产幼崽的每肝脏总酶活性较低。孕期喂食4%酪蛋白饮食的母鼠体重增加远低于喂食对照饮食的母鼠，所产幼崽体重也显著低于对照幼崽。少数在妊娠期喂食含或不含氨基酸补充剂的6%酪蛋白饮食的母鼠的繁殖性能与喂食对照饮食的母鼠相当。低蛋白摄入并未显著降低窝仔数。
