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姑息治疗和基本药物供应:泰国 2012 年全国调查。

Palliative care and essential drug availability: Thailand national survey 2012.

机构信息

Department of Social Medicine, Maesot General Hospital, Sripanich Road, Maesot, Tak, Thailand.

出版信息

J Palliat Med. 2013 May;16(5):546-50. doi: 10.1089/jpm.2012.0520.

Abstract

BACKGROUND

Palliative care in Thailand was not well established in the past, but it is better supported by many organizations at present. Despite the change in the situation, the availability of essential drugs for palliative care has not been well studied.

OBJECTIVE

Our aim was to update the medical community on the current situation of essential drug availability for palliative care in Thai hospitals.

METHODS

The International Association for Hospice and Palliative Care (IAHPC) list of 34 essential drugs for palliative care was used in this survey.

RESULTS

Five hundred and fifty-five hospitals replied to the questionnaire (response rate 57%). Eleven of the 24 nonopioid drugs were available above 90% in all hospitals. However, nonopioid drugs generally were less available in community hospitals (CH) and general hospitals (GH) than in large hospitals (LH). Tramadol was the most available weak opioid. Injectable morphine was the most available form of strong opioid in Thailand (96.9%). For the overall picture of oral morphine, immediate-release morphine was a less available form than the controlled-release form (32.2% versus 51.0%). Controlled-release oral morphine had a nearly two-fold better availability than immediate-release oral morphine in CH, GH, and LH, that is, cancer centers (CC), medical school hospitals (MH), regional hospitals (RH), and other government hospitals. In contrast, in private hospitals (PH), there was no difference between the availability of the controlled-release form and the immediate-release form. Transdermal fentanyl and methadone were also less available in Thailand (14.6% versus 16.5%, respectively).

CONCLUSION

LH and PH have better overall nonopioid and opioid medication availability than CH and GH.

摘要

背景

过去,泰国的缓和医疗服务并不完善,但目前有许多组织提供支持。尽管情况有所改善,但缓和医疗所需的基本药物的供应情况仍未得到充分研究。

目的

我们旨在向医疗界介绍泰国医院目前提供缓和医疗基本药物的现状。

方法

本研究使用国际姑息治疗协会(IAHPC)确定的 34 种缓和医疗基本药物清单。

结果

共有 555 家医院对问卷做出了回应(回应率为 57%)。在所有医院中,11 种非阿片类药物中有 11 种的供应率超过 90%。然而,与大型医院相比,社区医院和综合医院的非阿片类药物供应普遍较少。曲马多是最可获得的弱阿片类药物。注射用吗啡是泰国最可获得的强阿片类药物(96.9%)。对于口服吗啡的总体情况,即释吗啡的可获得性低于控释吗啡(32.2%对 51.0%)。在社区医院、综合医院和大型医院,即癌症中心、医学院附属医院、地区医院和其他政府医院,控释口服吗啡的可获得性比即释口服吗啡好近两倍。相比之下,在私立医院,控释剂型和即释剂型的可获得性没有差异。经皮芬太尼和美沙酮在泰国的可获得性也较低(分别为 14.6%和 16.5%)。

结论

大型医院和私立医院的非阿片类药物和阿片类药物总体供应情况优于社区医院和综合医院。

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