通过生物测定法测定的氚化河豚毒素的纯度。
The purity of tritiated tetrodotoxin as determined by bioassay.
作者信息
Levinson S R
出版信息
Philos Trans R Soc Lond B Biol Sci. 1975 Jun 10;270(908):337-48. doi: 10.1098/rstb.1975.0013.
PMID:238232
Abstract
The radioactivity binding of a tritiated tetrodotoxin preparation to an electric organ particulate fraction was compared with the binding of biological activity as determined by biological assay. This comparison shows that the chromatographically homogeneous toxin contained a large proportion of radioactive impurities which bind nonspecifically to the electroplax preparation.
摘要
将氚化河豚毒素制剂与电鳗器官微粒部分的放射性结合与通过生物测定法确定的生物活性结合进行了比较。这种比较表明，色谱纯的毒素含有大量放射性杂质，这些杂质会非特异性地与电板制剂结合。
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