Javadi Mohammad-Ali, Feizi Sepehr, Moein Hamid-Reza
Ophthalmic Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
J Ophthalmic Vis Res. 2013 Jan;8(1):39-46.
To determine the clinical outcomes of simultaneous penetrating keratoplasty (PK), cataract removal and intraocular lens implantation (triple procedure), and to compare the safety and efficacy of two different cataract extraction techniques during the course of PK.
This retrospective comparative study was conducted on patients who had undergone a triple procedure. The technique of cataract extraction was either open- sky extracapsular cataract extraction (ECCE) or phacoemulsification (PE). In the ECCE group, the posterior chamber intraocular lens (PCIOL) was implanted in the ciliary sulcus, while in the PE group PCIOLs were fixated within the capsular bag. Outcome measures included best spectacle corrected visual acuity (BSCVA), refractive results, graft clarity and complications.
Seventy-six eyes of 69 consecutive patients with mean age of 61.4±14.2 years were enrolled. Mean follow-up period was 61.4±37.2 months over which mean BSCVA was significantly improved from 1.40±0.68 to 0.44±0.33 LogMAR (P<0.001). Mean postoperative spherical equivalent refractive error was -2.13±3.02 D, which significantly differed from the target refraction (-0.73±0.29 D, P=0.004). At final follow-up, 89.5% of the corneal grafts remained clear.
The triple procedure is a safe and effective approach to restore vision in patients with coexisting corneal pathologies and cataracts. However, unacceptable postoperative refractive error can be anticipated.
确定穿透性角膜移植术(PK)、白内障摘除及人工晶状体植入同期手术(三联手术)的临床效果,并比较PK过程中两种不同白内障摘除技术的安全性和有效性。
对接受三联手术的患者进行这项回顾性比较研究。白内障摘除技术为开放式囊外白内障摘除术(ECCE)或超声乳化白内障吸除术(PE)。在ECCE组,后房型人工晶状体(PCIOL)植入睫状沟,而在PE组,PCIOL固定于囊袋内。观察指标包括最佳矫正视力(BSCVA)、屈光结果、植片清晰度及并发症。
纳入69例连续患者的76只眼,平均年龄61.4±14.2岁。平均随访期为61.4±37.2个月,在此期间,平均BSCVA从1.40±0.68显著提高至0.44±0.33 LogMAR(P<0.001)。术后平均球镜等效屈光不正为-2.13±3.02 D,与目标屈光不正(-0.73±0.29 D,P=0.004)有显著差异。在末次随访时,角膜植片89.5%保持透明。
三联手术是恢复合并角膜病变和白内障患者视力的一种安全有效的方法。然而,术后可能出现不可接受的屈光不正。