Department of Laboratory Medicine, National University Hospital, Singapore.
PLoS One. 2013 Jun 24;8(6):e66663. doi: 10.1371/journal.pone.0066663. Print 2013.
Hospital isolation rooms are vital for the containment (when under negative pressure) of patients with, or the protection (when under positive pressure) of patients, from airborne infectious agents. Such facilities were essential for the management of highly contagious patients during the 2003 severe acute respiratory syndrome (SARS) outbreaks and the more recent 2009 A/H1N1 influenza pandemic. Many different types of door designs are used in the construction of such isolation rooms, which may be related to the space available and affordability. Using colored food dye as a tracer, the qualitative effects of door-opening motions on the dissemination of potentially contaminated air into and out of a single isolation room were visualized and filmed using Reynolds-number-equivalent, small-scale, water-tank models fitted with programmable door-opening and moving human figure motions. Careful scaling considerations involved in the design and construction of these water-tank models enabled these results to be accurately extrapolated to the full-scale situation. Four simple types of door design were tested: variable speed single and double, sliding and hinged doors, in combination with the moving human figure. The resulting video footage was edited, synchronized and presented in a series of split-screen formats. From these experiments, it is clear that double-hinged doors pose the greatest risk of leakage into or out of the room, followed by (in order of decreasing risk) single-hinged, double-sliding and single-sliding doors. The relative effect of the moving human figure on spreading any potential contamination was greatest with the sliding doors, as the bulk airflows induced were large relative to those resulting from these door-opening motions. However, with the hinged doors, the airflows induced by these door-opening motions were significantly greater. Further experiments involving a simulated ventilated environment are required, but from these findings alone, it appears that sliding-doors are far more effective for hospital isolation room containment.
医院隔离病房对于控制(负压时)或保护(正压时)患者免受空气传播感染源的影响至关重要。在 2003 年严重急性呼吸综合征(SARS)爆发和最近的 2009 年 A/H1N1 流感大流行期间,这些设施对于管理高度传染性患者是必不可少的。在建造这些隔离病房时,使用了许多不同类型的门设计,这可能与可用空间和可负担性有关。使用彩色食用染料作为示踪剂,使用雷诺数等效的小型水箱模型可视化和拍摄了开门运动对潜在污染空气进出单个隔离病房的传播的定性影响,这些水箱模型配备了可编程开门和移动人体模型运动。在设计和建造这些水箱模型时,需要仔细考虑缩放因素,以使这些结果能够准确外推到全尺寸情况。测试了四种简单的门设计类型:变速单门和双门、滑动门和铰链门,以及移动人体模型。对所得的视频片段进行编辑、同步并以一系列分屏格式呈现。从这些实验中可以清楚地看出,双铰链门对进出房间的泄漏风险最大,其次是(风险递减顺序)单铰链、双滑动和单滑动门。移动人体模型对传播任何潜在污染的相对影响在滑动门中最大,因为所诱导的空气流相对于这些开门运动的结果较大。然而,对于铰接门,这些开门运动所诱导的空气流明显更大。需要进一步进行涉及模拟通风环境的实验,但仅从这些发现来看,滑动门对于医院隔离病房的隔离效果要好得多。