Institute for Complex Molecular Systems, Eindhoven University of Technology, P.O. Box 513, 5600 MB Eindhoven, The Netherlands.
J Am Chem Soc. 2013 Jul 31;135(30):11159-64. doi: 10.1021/ja403745w. Epub 2013 Jul 18.
In natural systems, highly synergistic non-covalent interactions among biomolecular components exert mesoscopic control over hierarchical assemblies. We herein present a multicomponent self-assembly strategy to tune hierarchical supramolecular polymer architectures in water using highly affine and directional ureidopyrimidinone-poly(ethylene glycol)s (UPy-PEG). Using scattering methods and oscillatory rheology, we observe the structural and mechanical regulation of entangled monofunctional UPy-PEG fibrils by cross-linking bifunctional UPy-PEG fibrils. This supramolecular mixing approach opens the door to a range of subtly distinct materials for chemical and biological applications.
在自然系统中，生物分子成分之间高度协同的非共价相互作用对层次组装施加介观控制。在此，我们提出了一种多组分自组装策略，使用高度亲和和定向的脲嘧啶嘧啶酮-聚乙二醇（UPy-PEG）在水中调节分级超分子聚合物结构。通过散射方法和振荡流变学，我们观察到通过交联双官能 UPy-PEG 纤维来调节缠结的单官能 UPy-PEG 纤维的结构和力学性能。这种超分子混合方法为化学和生物应用开辟了一系列微妙不同的材料。
