Lane S, Doherty M, Powell R J
Department of Immunology, Queen's Medical Centre, Nottingham.
Ann Rheum Dis. 1990 Jun;49(6):405-6. doi: 10.1136/ard.49.6.405.
A young man is reported with recurrent Staphylococcus aureus joint sepsis associated with dermatomyositis. His dermatomyositis failed to resolve on treatment with antimicrobial agents alone, indicating that if staphylococcal infection was the triggering event for the dermatomyositis then the subsequent process was apparently self perpetuating, requiring cytotoxic agents for its control. This case can be interpreted as possible further evidence for the triggering of autoimmune disease by infective agents.
据报道,一名患有复发性金黄色葡萄球菌关节败血症并伴有皮肌炎的年轻男子。单独使用抗菌药物治疗后,他的皮肌炎并未缓解,这表明如果葡萄球菌感染是皮肌炎的触发因素,那么随后的病程显然会自我延续,需要使用细胞毒性药物来控制。该病例可被视为感染因子引发自身免疫性疾病的可能进一步证据。