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习惯性午睡时间较长与老年人空腹血糖受损和糖尿病风险增加相关:来自东风-同济退休工人队列的研究结果。

Longer habitual afternoon napping is associated with a higher risk for impaired fasting plasma glucose and diabetes mellitus in older adults: results from the Dongfeng-Tongji cohort of retired workers.

机构信息

Ministry of Education Key Laboratory of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, China; Department of Maternal and Child Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, China.

出版信息

Sleep Med. 2013 Oct;14(10):950-4. doi: 10.1016/j.sleep.2013.04.015. Epub 2013 Jul 3.

DOI:10.1016/j.sleep.2013.04.015
PMID:23831240
Abstract

OBJECTIVES

Afternoon napping is a common habit in China. We used data obtained from the Dongfeng-Tongji cohort to examine if duration of habitual afternoon napping was associated with risks for impaired fasting plasma glucose (IFG) and diabetes mellitus (DM) in a Chinese elderly population.

METHODS

A total of 27,009 participants underwent a physical examination, laboratory tests, and face-to-face interview. They were categorized into four groups according to nap duration (no napping, <30, 30 to <60, 60 to <90, and > or =90 min). Logistic regression models were used to examine the odds ratios (ORs) of napping duration with IFG and DM.

RESULTS

Of the participants, 18,515 (68.6%) reported regularly taking afternoon naps. Those with longer nap duration had considerably higher prevalence of IFG and DM. Napping duration was associated in a dose-dependent manner with IFG and DM (P<.001). After adjusting for possible confounders, longer nap duration (>60 min; all P<.05) was still significantly associated with increased risk for IFG, and longer nap duration (>30 min) was associated with increased risk for DM; however, this finding was not significant in the group with a nap duration of 60-90 min.

CONCLUSIONS

Longer habitual afternoon napping was associated with a moderate increase for DM risk, independent of several covariates. This finding suggests that longer nap duration may represent a novel risk factor for DM and higher blood glucose levels.

摘要

目的

午睡在中国是一种常见的习惯。我们利用来自东风-同济队列的数据,研究中国老年人群中习惯性午睡时间与空腹血糖受损(IFG)和糖尿病(DM)风险的相关性。

方法

共有 27009 名参与者接受了体检、实验室检查和面对面访谈。他们根据午睡时间(无午睡、<30 分钟、30-<60 分钟、60-<90 分钟和≥90 分钟)被分为四组。采用 logistic 回归模型,检验午睡时间与 IFG 和 DM 的比值比(OR)。

结果

在参与者中,18515 人(68.6%)报告经常进行午后午睡。午睡时间较长的人 IFG 和 DM 的患病率明显较高。午睡时间与 IFG 和 DM 呈剂量依赖性相关(P<.001)。在调整了可能的混杂因素后,较长的午睡时间(>60 分钟;均 P<.05)仍与 IFG 的风险增加显著相关,而较长的午睡时间(>30 分钟)与 DM 的风险增加相关;然而,午睡时间在 60-90 分钟之间的组中,这一发现并不显著。

结论

习惯性午睡时间较长与 DM 风险的中度增加相关,与多个协变量无关。这一发现表明,较长的午睡时间可能是 DM 和较高血糖水平的一个新的危险因素。

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