Corresponding author: School of Public Health, University of Chile, Av. Independencia 939, Santiago, Chile.
Alcohol Alcohol. 2013 Nov-Dec;48(6):729-36. doi: 10.1093/alcalc/agt066. Epub 2013 Jul 5.
The aim of the study was to estimate mortality and years of potential life lost (YPLL) attributable to alcohol consumption in 2009 in Chile.
The population considered for this study included those 15 years and over. Exposure to alcohol in the population was estimated by triangulating the records of alcohol per capita consumption in Chile with information from the Eighth National Study of Drugs in the General Population (2008). The effect of alcohol consumption on each cause of death (relative risk) was extracted from previously published meta-analyses. With this information we estimated the alcohol-attributable fraction (AAF) and deaths and YPLL due to alcohol consumption. The confidence intervals for the AAF were estimated with Monte Carlo sampling using the estimated variances of the exposure prevalence and relative effect.
The estimated total number of deaths attributable to alcohol consumption was 8753 (95% CI: 6257, 11,584) corresponding to 9.8% (95% CI: 7.01%, 12.98%) of all deaths in Chile in 2009. The total estimated YPLL attributable to alcohol were 195,475 (95% CI: 164,287, 227,726), corresponding to 21.5% (95% CI: 18.1%, 25.0%) of total YPLL for that year in Chile.
Alcohol consumption is a major risk factor and accounts for nearly one of ten deaths in Chile. These results may be used to guide the design of public health policies and evaluations.
本研究旨在估计 2009 年智利因饮酒导致的死亡率和潜在寿命损失年数(YPLL)。
本研究的研究对象为 15 岁及以上人群。通过将智利人均酒精消费量的记录与第八次普通人群毒品全国调查(2008 年)的信息进行三角定位,估算出人群中接触酒精的情况。从先前发表的荟萃分析中提取出饮酒对每种死因(相对风险)的影响。根据这些信息,我们估算了酒精归因分数(AAF)以及因饮酒导致的死亡人数和 YPLL。使用蒙特卡罗抽样法对 AAF 的置信区间进行了估计,方法是利用暴露流行率和相对效应的估计方差进行模拟。
估计有 8753 人(95%CI:6257,11584)的死亡可归因于饮酒,占 2009 年智利所有死亡人数的 9.8%(95%CI:7.01%,12.98%)。估计归因于酒精的总 YPLL 为 195475 人(95%CI:164287,227726),占智利当年总 YPLL 的 21.5%(95%CI:18.1%,25.0%)。
饮酒是一个主要的危险因素,占智利近十分之一的死亡人数。这些结果可用于指导公共卫生政策和评估的制定。