Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, 8635 West Third Street, Suite 1070, Los Angeles, CA 90048, USA.
Quant Imaging Med Surg. 2013 Jun;3(3):130-1. doi: 10.3978/j.issn.2223-4292.2013.06.05.
It is standard practice to presume that solid renal tumors are malignant and perform a nephrectomy without a biopsy. In many clinical situations, renal biopsies lack sufficient diagnostic accuracy to justify altering management. Lanzman and colleagues propose the use of arterial spin-labeling magnetic resonance imaging to assess renal histology and grade. They used histopathologic data as the reference standard, and reported a statistically significant difference in measured tumor perfusion between papillary renal tumor, oncocytomas, and all other histologic subtypes examined. If confirmed in larger studies, this imaging modality may play a role in triaging patients with solid renal masses for surgery or renal biopsy.
通常假定实体肾肿瘤为恶性，并在不进行活检的情况下进行肾切除术。在许多临床情况下，肾活检的诊断准确性不足以证明改变治疗方法是合理的。Lanzman 及其同事提出使用动脉自旋标记磁共振成像来评估肾组织学和分级。他们使用组织病理学数据作为参考标准，报告了在乳头状肾肿瘤、嗜酸细胞瘤和所有其他检查的组织学亚型之间测量的肿瘤灌注之间存在统计学显著差异。如果在更大的研究中得到证实，这种成像方式可能在为手术或肾活检对患有实体肾肿块的患者进行分类方面发挥作用。
