Aranceta Bartrina Javier, Pérez Rodrigo Carmen
Nutr Hosp. 2013 Jul;28 Suppl 4:95-105. doi: 10.3305/nh.2013.28.sup4.6802.
The aim of this review is to summarize the evidence available about the association between sugar consumption, especially sucrose, and the risk of different types of cancer.
A systematic review was conducted of key reports, systematic reviews, meta-analysis as well as big prospective studies published after 2007 January 1 thru 2012 December 31 about the association between sugar consumption, especially sucrose, and the risk of cancer.
Evidence of the association of the intake of mono and disaccharides with different types of cancer is insufficient or there is evidence of lack of association. There is only possible evidence of a positive relation between the intake of monosaccharides (fructose and glucose) and pancreatic cancer. Evidence about the association between monosaccharides intake and obesity is insufficient, as well as between the intake of sucrose or added sugars and the risk of obesity in adults and children. There is possible evidence of a positive association between glycemic index (GI) and colorectal cancer and that there is no association between GI and the risk of endometrial cancer, breast cancer and pancreas cancer.
More research is needed. Cohort studies are especially required and randomized intervention trials would be desirable, although these are difficult in this field.
本综述旨在总结关于糖摄入，尤其是蔗糖摄入与不同类型癌症风险之间关联的现有证据。
对2007年1月1日至2012年12月31日之后发表的关于糖摄入，尤其是蔗糖摄入与癌症风险之间关联的关键报告、系统评价、荟萃分析以及大型前瞻性研究进行了系统综述。
单糖和双糖摄入与不同类型癌症之间关联的证据不足，或有证据表明缺乏关联。仅有可能的证据表明单糖（果糖和葡萄糖）摄入与胰腺癌之间存在正相关。关于单糖摄入与肥胖之间的关联证据不足，蔗糖或添加糖摄入与成人及儿童肥胖风险之间的关联证据也不足。有可能的证据表明血糖生成指数（GI）与结直肠癌之间存在正相关，且GI与子宫内膜癌、乳腺癌和胰腺癌风险之间无关联。
需要更多研究。尤其需要队列研究，随机干预试验也很有必要，尽管在该领域开展此类试验存在困难。
