• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

相似文献

1
Single-photon sampling architecture for solid-state imaging sensors.用于固态成像传感器的单光子采样架构。
Proc Natl Acad Sci U S A. 2013 Jul 23;110(30):E2752-61. doi: 10.1073/pnas.1216318110. Epub 2013 Jul 8.
2
A CMOS SPAD Imager with Collision Detection and 128 Dynamically Reallocating TDCs for Single-Photon Counting and 3D Time-of-Flight Imaging.一种具有碰撞检测功能的 CMOS SPAD 成像器,以及 128 个可动态重新分配的 TDC,用于单光子计数和 3D 飞行时间成像。
Sensors (Basel). 2018 Nov 17;18(11):4016. doi: 10.3390/s18114016.
3
Sensitivity encoded silicon photomultiplier--a new sensor for high-resolution PET-MRI.灵敏度编码硅光电倍增管——一种用于高分辨率 PET-MRI 的新型传感器。
Phys Med Biol. 2013 Jul 21;58(14):4733-48. doi: 10.1088/0031-9155/58/14/4733. Epub 2013 Jun 20.
4
A novel depth-of-interaction block detector for positron emission tomography using a dichotomous orthogonal symmetry decoding concept.一种采用二分正交对称解码概念的用于正电子发射断层扫描的新型相互作用深度块探测器。
Phys Med Biol. 2016 Feb 21;61(4):1608-33. doi: 10.1088/0031-9155/61/4/1608. Epub 2016 Feb 2.
5
Architecture-Level Optimization on Digital Silicon Photomultipliers for Medical Imaging.数字硅光电倍增管在医学成像中的架构级优化
Sensors (Basel). 2021 Dec 24;22(1):122. doi: 10.3390/s22010122.
6
Theoretical investigation of the count rate capabilities of in-pixel amplifiers for photon counting arrays based on polycrystalline silicon TFTs.基于多晶硅 TFT 的光子计数阵列像素内放大器计数率性能的理论研究。
Med Phys. 2018 Oct;45(10):4418-4429. doi: 10.1002/mp.13128. Epub 2018 Sep 14.
7
CMOS Time-to-Digital Converters for Biomedical Imaging Applications.用于生物医学成像应用的CMOS时间数字转换器
IEEE Rev Biomed Eng. 2023;16:627-652. doi: 10.1109/RBME.2021.3092197. Epub 2023 Jan 5.
8
Effects of multiple-interaction photon events in a high-resolution PET system that uses 3-D positioning detectors.使用 3D 定位探测器的高分辨率 PET 系统中多次相互作用光子事件的影响。
Med Phys. 2010 Oct;37(10):5494-508. doi: 10.1118/1.3483262.
9
Compact pulse width modulation circuitry for silicon photomultiplier readout.用于硅光电倍增管读出的紧凑型脉冲宽度调制电路。
Phys Med Biol. 2013 Aug 7;58(15):5049-59. doi: 10.1088/0031-9155/58/15/5049. Epub 2013 Jul 8.
10
A Full Parallel Event Driven Readout Technique for Area Array SPAD FLIM Image Sensors.一种用于面阵单光子雪崩二极管荧光寿命成像(SPAD FLIM)图像传感器的全并行事件驱动读出技术。
Sensors (Basel). 2016 Jan 27;16(2):160. doi: 10.3390/s16020160.

引用本文的文献

1
Silicon single-photon avalanche diodes with nano-structured light trapping.具有纳米结构光捕获的硅单光子雪崩二极管。
Nat Commun. 2017 Sep 20;8(1):628. doi: 10.1038/s41467-017-00733-y.
2
A Note on the Minimax Solution for the Two-Stage Group Testing Problem.关于两阶段分组测试问题的极小极大解的一则注释。
Am Stat. 2015;69(1):45-52. doi: 10.1080/00031305.2014.983545. Epub 2014 Nov 17.

本文引用的文献

1
New constructions of one- and two-stage pooling designs.单阶段和两阶段合并设计的新构建
J Comput Biol. 2008 Mar;15(2):195-205. doi: 10.1089/cmb.2007.0195.

用于固态成像传感器的单光子采样架构。

Single-photon sampling architecture for solid-state imaging sensors.

机构信息

Department of Mathematics, Institute for Computational and Mathematical Engineering, Stanford University, Stanford, CA 94305, USA.

出版信息

Proc Natl Acad Sci U S A. 2013 Jul 23;110(30):E2752-61. doi: 10.1073/pnas.1216318110. Epub 2013 Jul 8.

DOI:10.1073/pnas.1216318110
PMID:23836643
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3725070/
Abstract

Advances in solid-state technology have enabled the development of silicon photomultiplier sensor arrays capable of sensing individual photons. Combined with high-frequency time-to-digital converters (TDCs), this technology opens up the prospect of sensors capable of recording with high accuracy both the time and location of each detected photon. Such a capability could lead to significant improvements in imaging accuracy, especially for applications operating with low photon fluxes such as light detection and ranging and positron-emission tomography. The demands placed on on-chip readout circuitry impose stringent trade-offs between fill factor and spatiotemporal resolution, causing many contemporary designs to severely underuse the technology's full potential. Concentrating on the low photon flux setting, this paper leverages results from group testing and proposes an architecture for a highly efficient readout of pixels using only a small number of TDCs. We provide optimized design instances for various sensor parameters and compute explicit upper and lower bounds on the number of TDCs required to uniquely decode a given maximum number of simultaneous photon arrivals. To illustrate the strength of the proposed architecture, we note a typical digitization of a 60 × 60 photodiode sensor using only 142 TDCs. The design guarantees registration and unique recovery of up to four simultaneous photon arrivals using a fast decoding algorithm. By contrast, a cross-strip design requires 120 TDCs and cannot uniquely decode any simultaneous photon arrivals. Among other realistic simulations of scintillation events in clinical positron-emission tomography, the above design is shown to recover the spatiotemporal location of 99.98% of all detected photons.

摘要

固态技术的进步使得能够开发出能够感应单个光子的硅光电倍增器传感器阵列。与高频时间数字转换器 (TDC) 相结合,这项技术为能够高精度记录每个检测到的光子的时间和位置的传感器开辟了前景。这种能力可以显著提高成像精度,特别是对于低光子通量应用,如光探测和测距以及正电子发射断层扫描。对片上读出电路的需求在填充因子和时空分辨率之间施加了严格的权衡,导致许多当代设计严重低估了该技术的全部潜力。本文专注于低光子通量设置,利用群体测试的结果,提出了一种使用少量 TDC 对像素进行高效读出的架构。我们为各种传感器参数提供了优化的设计实例,并计算了唯一解码给定最大同时光子到达数所需的 TDC 数的明确上限和下限。为了说明所提出架构的优势,我们注意到仅使用 142 个 TDC 对典型的 60×60 光电二极管传感器进行数字化。该设计使用快速解码算法保证了多达四个同时光子到达的注册和唯一恢复。相比之下,交叉条设计需要 120 个 TDC,并且不能唯一解码任何同时的光子到达。在临床正电子发射断层扫描中闪烁事件的其他实际模拟中,上述设计被证明可以恢复所有检测到的光子的 99.98%的时空位置。