圆眼燕鱼（Platax orbicularis）的巨细胞病毒感染

Megalocytivirus infection in orbiculate batfish Platax orbicularis.

作者信息

Sriwanayos Preeyanan, Francis-Floyd Ruth, Stidworthy Mark F, Petty Barbara D, Kelley Karen, Waltzek Thomas B

机构信息

Program in Fisheries and Aquatic Sciences, School of Forestry Resources and Conservation, University of Florida, Gainesville, Florida 32653, USA.

出版信息

Dis Aquat Organ. 2013 Jul 9;105(1):1-8. doi: 10.3354/dao02594.

DOI:10.3354/dao02594

PMID:23836765

Abstract

Megalocytiviruses cause systemic disease in both marine and freshwater fishes, negatively impacting ornamental and food fish aquaculture. In this report, we characterize a megalocytivirus infection in a captive marine ornamental fish, the orbiculate batfish Platax orbicularis. Histologic examination revealed cytomegalic cells characterized by strongly basophilic granular intracytoplasmic inclusions within various organs. Transmission electron microscopy revealed icosahedral virus particles within the cytoplasm of cytomegalic cells consistent with an iridovirus infection. Analysis of the major capsid protein gene sequence confirmed that the orbiculate batfish virus is a member of the family Iridoviridae and is identical to the only other megalocytivirus reported from a marine ornamental fish, the Banggai cardinalfish Pterapogon kauderni iridovirus.

摘要

巨细胞病毒可在海水鱼和淡水鱼中引发全身性疾病，对观赏鱼和食用鱼养殖产生负面影响。在本报告中，我们描述了一种圈养海水观赏鱼——圆眼燕鱼（Platax orbicularis）感染巨细胞病毒的情况。组织学检查显示，在各个器官中存在以强烈嗜碱性颗粒状胞质内包涵体为特征的巨细胞。透射电子显微镜显示，巨细胞的细胞质内存在二十面体病毒颗粒，与虹彩病毒感染相符。主要衣壳蛋白基因序列分析证实，圆眼燕鱼病毒是虹彩病毒科的成员，并且与另一种从海水观赏鱼——班盖刺尾鱼（Pterapogon kauderni）虹彩病毒中报道的巨细胞病毒完全相同。