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基于运动肌电图数据存档系统的肌肉松弛效果管理调查:一种回顾性定量与情境质量控制方法。

Survey of muscle relaxant effects management with a kinemyographic-based data archiving system: a retrospective quantitative and contextual quality control approach.

作者信息

Motamed Cyrus, Bourgain Jean Louis, D'Hollander Alain

机构信息

Department of Anaesthesia, Institut Gustave Roussy, Villejuif, France,

出版信息

J Clin Monit Comput. 2013 Dec;27(6):669-76. doi: 10.1007/s10877-013-9491-0. Epub 2013 Jul 10.

Abstract

In a retrospective quality control study of muscle relaxant management, we assessed unbiased files provided by an automatic archiving system using quantitative monitoring generated by a kinemyographic transducer and suggest improvements for a possible future design. 200 randomly selected files were double checked to collect the values of twitch height ratio (THr), train of four ratio (TOFr) and TOF count in four periods: references values acquisition (REF), maximal level of paralysis, paralysis maintenance, pre-tracheal extubation residual paralysis assessment (RPA). The parameter values were selected according to period-specific predefined rules. A quantitative quality control was based upon standardized cut-offs values. A contextual quality control was based upon the detection of "difficult-to-interpret" episodes. Results were expressed on a descriptive basis only. For the REF period, THrs and TOFrs were lacking in, respectively, 47 and 18 of the 200 recordings analysed. A starting TOFr above 0.90 existed in 119 files. Concomitant THrs and TOFrs >0.90 were evidenced 93 times. During RPA period, TOFr >0.90 was recorded on 82 occasions. The optimal combination of THr >0.80 and TOFr >0.90 was detected in 30 files only. Presence of "difficult to interpret" episodes started with 18 files for the REF period and increased to 42, 86 and 52 in the subsequent ones most of them probably related to the absence of initial calibration procedure. In the real life conditions, a near to optimal quality control is not always observable with the quantitative neuromuscular monitoring studied. To improve the NMT monitoring, the calibration of the sensor should be performed vigorously by the anaesthesia provider and the quality of this calibration must be displayed on the screen of the monitor.

摘要

在一项关于肌肉松弛剂管理的回顾性质量控制研究中,我们使用运动描记换能器产生的定量监测,评估了自动存档系统提供的无偏差文件,并为未来可能的设计提出改进建议。随机选择200份文件进行二次检查,以收集四个时期的颤搐高度比值(THr)、四个成串刺激比值(TOFr)和四个成串刺激计数的值:参考值采集(REF)、最大麻痹水平、麻痹维持、气管插管前残余麻痹评估(RPA)。参数值根据特定时期的预定义规则进行选择。定量质量控制基于标准化的临界值。情境质量控制基于对“难以解释”事件的检测。结果仅以描述性方式呈现。在REF时期,分析的200份记录中分别有47份和18份缺少THr和TOFr。119份文件中起始TOFr高于0.90。同时出现THr和TOFr>0.90的情况有93次。在RPA时期,TOFr>0.90被记录了82次。仅在30份文件中检测到THr>0.80和TOFr>0.90的最佳组合。“难以解释”事件在REF时期始于18份文件,在随后的时期增加到42份、86份和52份,其中大多数可能与缺乏初始校准程序有关。在实际情况中,所研究的定量神经肌肉监测并非总能实现近乎最佳的质量控制。为改善神经肌肉监测,麻醉提供者应严格进行传感器校准,且校准质量必须显示在监测仪屏幕上。

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