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儿童性虐待与青少年及成人自杀的病理生理学

Child sexual abuse and the pathophysiology of suicide in adolescents and adults.

作者信息

O'Brien Betsy S, Sher Leo

出版信息

Int J Adolesc Med Health. 2013;25(3):201-5. doi: 10.1515/ijamh-2013-0053.

DOI:10.1515/ijamh-2013-0053
PMID:23843572
Abstract

BACKGROUND

Child sexual abuse (CSA) is widespread and is associated with various psychopathologies, including Axis I and II disorders, maladaptive and impulsive behaviors, and suicidal behavior in adolescence and adults. The pathophysiology of this association is not well understood; however, it is clear that suicidal behavior in individuals with a history of CSA is a significant social and medical problem that warrants further investigation.

METHODS

An electronic search of the major behavioral science databases (limited to the most recent studies in the last 20 years) was conducted to retrieve studies detailing the social, epidemiological, and clinical characteristics of child sexual trauma and their relation to suicidal behavior in adolescents and adults.

RESULTS

Studies indicate that CSA is related to an increase in Axis I and II diagnoses, including depression, post-traumatic stress disorder, conduct disorders, eating disorders, alcohol and drug abuse, panic disorders, and borderline personality disorder. CSA not just related to an increase in impulsivity and risky behaviors, it has also been linked to an increase in suicidality as well.

CONCLUSION

CSA makes both direct and indirect contributions to suicidal behavior. It is a complex process involving multiple variables, which include psychopathology, maladaptive personality features and the direct contribution of CSA itself. Psychopathologies, such as impulsivity and mood and personality disorders, may modulate the relationship between CSA and suicidal behavior. Some preventive measures for decreasing the prevalence of CSA and suicidality may include education as well as increased access to mental health services.

摘要

背景

儿童性虐待(CSA)普遍存在,且与多种精神病理学问题相关,包括轴I和轴II障碍、适应不良和冲动行为,以及青少年和成年人的自杀行为。这种关联的病理生理学尚未得到很好的理解;然而,很明显,有CSA病史的个体的自杀行为是一个重大的社会和医学问题,值得进一步研究。

方法

对主要行为科学数据库进行电子检索(限于过去20年的最新研究),以检索详细描述儿童性创伤的社会、流行病学和临床特征及其与青少年和成年人自杀行为关系的研究。

结果

研究表明,CSA与轴I和轴II诊断的增加有关,包括抑郁症、创伤后应激障碍、品行障碍、饮食失调、酒精和药物滥用、惊恐障碍和边缘性人格障碍。CSA不仅与冲动性和危险行为的增加有关,还与自杀倾向的增加有关。

结论

CSA对自杀行为有直接和间接的影响。这是一个涉及多个变量的复杂过程,这些变量包括精神病理学、适应不良的人格特征以及CSA本身的直接影响。冲动性、情绪和人格障碍等精神病理学问题可能会调节CSA与自杀行为之间的关系。一些降低CSA和自杀倾向患病率的预防措施可能包括教育以及增加获得心理健康服务的机会。

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