Department of Psychiatry and Human Behavior, Brown University, Providence, RI 02906, USA.
Psychol Med. 2013 May;43(5):983-93. doi: 10.1017/S0033291712001912. Epub 2012 Aug 30.
The aim of this study was to examine prospective predictors of suicide events, defined as suicide attempts or emergency interventions to reduce suicide risk, in 119 adolescents admitted to an in-patient psychiatric unit for suicidal behaviors and followed naturalistically for 6 months. Method Structured diagnostic interviews and self-report instruments were administered to adolescent participants and their parent(s) to assess demographic variables, history of suicidal behavior, psychiatric disorders, family environment and personality/temperament.
Baseline variables that significantly predicted time to a suicide event during follow-up were Black race, high suicidal ideation in the past month, post-traumatic stress disorder (PTSD), childhood sexual abuse (CSA), borderline personality disorder (BPD), low scores on positive affectivity, and high scores on aggression. In a multivariate Cox regression analysis, only Black race, CSA, positive affect intensity and high aggression scores remained significant.
Our findings suggest the following for adolescent populations: (1) in a very high-risk population, risk factors for future attempts may be more difficult to ascertain and some established risk factors (e.g. past suicide attempt) may not distinguish as well; and (2) cross-cutting constructs (e.g. affective and behavioral dysregulation) that underlie multiple psychiatric disorders may be stronger predictors of recurrent suicide events than psychiatric diagnoses. Our finding with respect to positive affect intensity is novel and may have practical implications for the assessment and treatment of adolescent suicide attempters.
本研究旨在探讨 119 名因自杀行为住院的青少年在 6 个月的自然随访中发生自杀事件(定义为自杀未遂或紧急干预以降低自杀风险)的前瞻性预测因素。方法:对青少年参与者及其父母进行结构化诊断访谈和自我报告工具,以评估人口统计学变量、自杀行为史、精神障碍、家庭环境和人格/气质。
在随访期间预测自杀事件时间的基线变量有:黑人种族、过去一个月内有强烈自杀意念、创伤后应激障碍(PTSD)、儿童期性虐待(CSA)、边缘型人格障碍(BPD)、积极情感评分低和攻击性评分高。在多变量 Cox 回归分析中,只有黑人种族、CSA、积极情感强度和高攻击性评分仍然显著。
我们的研究结果表明,对于青少年人群:(1)在一个极高风险人群中,未来尝试的风险因素可能更难确定,一些既定的风险因素(例如过去的自杀尝试)可能无法很好地区分;(2)跨领域的结构(例如情感和行为失调)可能是多次自杀事件的更强预测因素,而不是精神障碍诊断。我们关于积极情感强度的发现是新颖的,可能对青少年自杀未遂者的评估和治疗具有实际意义。