Aksoy Ülkü, Aksoy Hüseyin, Açmaz Gökhan, Babayiğit Mustafa, Kandemir Ömer
Department of Obstetrics and Gynecology, Kayseri Training and Education Hospital of Medicine , Kayseri , Turkey .
Hypertens Pregnancy. 2013 Nov;32(4):401-9. doi: 10.3109/10641955.2013.810239. Epub 2013 Jul 11.
To evaluate the significance of umbilical cord chitotriosidase concentrations in pregnancies with mild preeclampsia and explore the relationship between fetal chitotriosidase levels and fetal blood flow velocity.
The study population included control group (n=40) and study group with mild preeclampsia (n=40). Umbilical cord blood samples were collected immediately after delivery. Umbilical artery (UA) flow velocity waveform was determined just before delivery.
Umbilical cord chitotriosidase levels and UA S/D rate were significantly high in preeclamptic group.
Chitotriosidase may be useful biochemical marker of fetal compromise that reflects the severity of fetoplacental blood flow resistance in pregnancies complicated by preeclampsia.
评估脐带壳三糖苷酶浓度在轻度子痫前期妊娠中的意义，并探讨胎儿壳三糖苷酶水平与胎儿血流速度之间的关系。
研究人群包括对照组（n = 40）和轻度子痫前期研究组（n = 40）。分娩后立即采集脐带血样本。在分娩前测定脐动脉（UA）血流速度波形。
子痫前期组脐带壳三糖苷酶水平和UA S/D率显著升高。
壳三糖苷酶可能是反映子痫前期妊娠中胎儿胎盘血流阻力严重程度的胎儿窘迫的有用生化标志物。
