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When too much of a good thing is bad: chronic oxytocin, development, and social impairments.

作者信息

Young Larry J

机构信息

Center for Translational Social Neuroscience, Department of Psychiatry and Behavioral Neuroscience, Yerkes National Primate Research Center, Emory University, Atlanta, Georgia, USA.

出版信息

Biol Psychiatry. 2013 Aug 1;74(3):160-1. doi: 10.1016/j.biopsych.2013.05.015.

DOI:10.1016/j.biopsych.2013.05.015
PMID:23845581
Abstract
摘要

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When too much of a good thing is bad: chronic oxytocin, development, and social impairments.过犹不及：慢性催产素、发育与社会功能障碍
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[Oxytocin: evidence for a therapeutic potential of the social neuromodulator].[催产素：社交神经调节剂治疗潜力的证据]
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Septal oxytocin administration impairs peer affiliation via V1a receptors in female meadow voles.在雌性草甸田鼠中，通过室旁核给予催产素会通过V1a受体损害同伴依恋。
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Centrally-administered oxytocin promotes preference for familiar objects at a short delay in ovariectomized female rats.中枢给予的催产素可促进去卵巢雌性大鼠在短时间延迟后对熟悉物体产生偏好。
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Oxytocin receptors modulate a social salience neural network in male prairie voles.催产素受体调节雄性草原田鼠的社会显著性神经网络。
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Oxytocin but not naturally occurring variation in caregiver touch associates with infant social orienting.催产素而非照顾者触摸中的自然变异与婴儿的社会定向有关。
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Chronic oxytocin administration as a tool for investigation and treatment: A cross-disciplinary systematic review.
慢性催产素给药作为一种研究和治疗工具：跨学科系统评价。
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The Impact of Early Postnatal and Juvenile Social Environments on the Effects of Chronic Intranasal Oxytocin in the Prairie Vole.产后早期和幼年社会环境对草原田鼠慢性鼻内注射催产素效果的影响
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Oxytocin and Eating Disorders: A Narrative Review on Emerging Findings and Perspectives.催产素与进食障碍：新兴研究发现与展望的综述。
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The oxytocin system promotes resilience to the effects of neonatal isolation on adult social attachment in female prairie voles.催产素系统可增强雌性草原田鼠成年后对新生期隔离所致社交依恋影响的恢复力。
Transl Psychiatry. 2015 Jul 21;5(7):e606. doi: 10.1038/tp.2015.73.
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Oxytocin receptor gene methylation: converging multilevel evidence for a role in social anxiety.催产素受体基因甲基化：关于其在社交焦虑中作用的多层面汇聚证据
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Developmental perspectives on oxytocin and vasopressin.催产素和加压素的发育视角
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Inhaled oxytocin increases positive social behaviors in newborn macaques.吸入催产素可增加新生猕猴的积极社交行为。
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