Department of Radiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.
J Pediatr Surg. 2013 Jun;48(6):E19-22. doi: 10.1016/j.jpedsurg.2013.04.007.
Hepatic adenomas are rare benign liver tumors seen most commonly in young women on oral contraceptives. Large hepatic adenomas are at risk of malignant transformation and require treatment in select patients, usually by surgical resection. Radiofrequency ablation (RFA) has become a widely used and accepted tool for the curative treatment of small primary hepatocellular carcinomas in adults; however, its use in the treatment of other liver lesions, such as hepatic adenoma, has only recently been described. Use of RFA for liver lesions in pediatric population remains novel. We present a case of large hepatic adenoma successfully treated with RFA in a child with chronic liver disease secondary to alpha-1-antitrypsin deficiency. RFA may be an attractive option in pediatric liver tumor management in selected cases because of its less invasive characteristics.
肝腺瘤是一种罕见的良性肝肿瘤，多见于口服避孕药的年轻女性。大的肝腺瘤有恶性转化的风险，需要在某些患者中进行治疗，通常采用手术切除。射频消融（RFA）已成为成人小原发性肝细胞癌的一种广泛应用和接受的治疗方法；然而，其在治疗其他肝病变，如肝腺瘤方面的应用最近才被描述。RFA 在儿科人群中的肝病变中的应用仍然是新颖的。我们报告了一例α-1-抗胰蛋白酶缺乏症继发慢性肝病的儿童中成功应用 RFA 治疗的大肝腺瘤病例。由于 RFA 的侵袭性较小，因此它可能是某些情况下儿童肝肿瘤治疗的一个有吸引力的选择。
