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The efficacy and roles of combining temozolomide with whole brain radiotherapy in protection neurocognitive function and improvement quality of life of non-small-cell lung cancer patients with brain metastases.替莫唑胺联合全脑放疗在保护非小细胞肺癌脑转移患者神经认知功能及提高生活质量方面的疗效和作用。
BMC Cancer. 2017 Jan 10;17(1):42. doi: 10.1186/s12885-016-3017-3.
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RADVAN: a randomised phase 2 trial of WBRT plus vandetanib for melanoma brain metastases - results and lessons learnt.RADVAN：一项关于全脑放疗联合凡德他尼治疗黑色素瘤脑转移的随机2期试验——结果与经验教训
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本文引用的文献

1
A phase 3 trial of whole brain radiation therapy and stereotactic radiosurgery alone versus WBRT and SRS with temozolomide or erlotinib for non-small cell lung cancer and 1 to 3 brain metastases: Radiation Therapy Oncology Group 0320.一项针对非小细胞肺癌和 1 至 3 个脑转移瘤患者的单纯全脑放疗和立体定向放射外科与 WBRT 和 SRS 联合替莫唑胺或厄洛替尼的 3 期临床试验：放射治疗肿瘤学组 0320。
Int J Radiat Oncol Biol Phys. 2013 Apr 1;85(5):1312-8. doi: 10.1016/j.ijrobp.2012.11.042. Epub 2013 Feb 4.
2
Whole-brain radiation therapy plus concomitant temozolomide for the treatment of brain metastases from non-small-cell lung cancer: a randomized, open-label phase II study.全脑放疗联合替莫唑胺治疗非小细胞肺癌脑转移：一项随机、开放标签的 II 期研究。
Clin Lung Cancer. 2010 May;11(3):176-81. doi: 10.3816/CLC.2010.n.022.
3
Phase II randomized trial of temozolomide and concurrent radiotherapy in patients with brain metastases.替莫唑胺与同步放疗用于脑转移瘤患者的II期随机试验
J Clin Oncol. 2002 Sep 1;20(17):3644-50. doi: 10.1200/JCO.2002.04.140.

A phase 3 trial of whole brain radiation therapy and stereotactic radiosurgery alone versus WBRT & SRS with temozolomide or erlotinib for non-small cell lung cancer and 1 to 3 brain metastases: Radiation Therapy Oncology Group 0320: in regard to Sperduto et al.

作者信息

Robins H Ian, O'Neill Anne, Mehta Minesh, Grossman Stuart

出版信息

Int J Radiat Oncol Biol Phys. 2013 Aug 1;86(5):809-10. doi: 10.1016/j.ijrobp.2013.03.040.

DOI:10.1016/j.ijrobp.2013.03.040
PMID:23845832
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4086629/
Abstract
摘要