英国与朝觐相关的A群脑膜炎球菌病

Group A meningococcal disease in England associated with the Haj.

作者信息

Jones D M, Sutcliffe E M

机构信息

Regional Public Health Laboratory, Withington Hospital, Manchester, U.K.

出版信息

J Infect. 1990 Jul;21(1):21-5. doi: 10.1016/0163-4453(90)90577-u.

DOI:10.1016/0163-4453(90)90577-u

PMID:2384679

Abstract

An outbreak of group A meningococcal infection amongst the Muslim population in England followed the outbreak of meningococcal disease associated with the 1987 Haj to Mecca. There were 18 primary cases amongst pilgrims returning from Mecca and 15 subsequent cases among Muslims over the following 19 months. The meningococcal strains were shown to be of the same clone as strains from the Mecca outbreak by possession of an outer membrane protein PI.9. Strains of this group A clone (A III-I) had only rarely been encountered in England before this outbreak.

摘要

在与1987年前往麦加的朝觐相关的脑膜炎球菌病疫情爆发之后，英格兰穆斯林人群中出现了A群脑膜炎球菌感染疫情。从麦加归来的朝圣者中有18例原发性病例，在接下来的19个月里，穆斯林人群中又出现了15例后续病例。通过拥有外膜蛋白PI.9，这些脑膜炎球菌菌株被证明与麦加疫情中的菌株属于同一克隆。在此次疫情爆发之前，这种A群克隆（A III-I）菌株在英格兰很少见。