Sanz París Alejandro, García José M, Gómez-Candela Carmen, Burgos Rosa, Martín Ángela, Matía Pilar
Nutrition Department of University Hospital Miguel Servet, Zaragoza, Spain.
Nutr Hosp. 2013 May-Jun;28(3):592-9. doi: 10.3305/nh.2013.28.3.6472.
Malnutrition prevalence is unknown among elderly patients with diabetes mellitus. Our objectives were to determine malnutrition prevalence in elderly in patients with diabetes, and to describe their impact on prognosis.
An observational multicenter study was conducted in 35 Spanish hospitals. Malnutrition was assessed with the Mini Nutritional Assessment (MNA) tool. Patients were followed until discharge.
1,090 subjects were included (78 ± 7.1 years; 50% males). 39.1% had risk of malnutrition, and 21.2% malnutrition. A 15.5% of the malnourished subjects and 31.9 % of those at risk had a BMI ≥ 30 kg/m(2). In multivariate analysis, female gender (OR = 1.38; 95% CI: 1.19-1.11), age (OR = 1.04; 95% CI: 1.02-1.06) and presence of diabetic complications (OR = 1.97; 95% CI: 1.52-2.56) were associated with malnutrition. Length of stay (LOS) was longer in at-risk and malnourished patients than in well-nourished (12.7 ± 9.9 and 15.7 ± 12.8 days vs 10.7 ± 9.9 days; p < 0.0001). After adjustment by age and gender, MNA score (OR = 0.895; 95% CI 0.814-0.985) and albumin (OR = 0.441; 95% CI 0.212-0.915) were associated with mortality. MNA score was associated with the probability of home discharge (OR = 1.150; 95% CI 1.084-1.219).
A high prevalence of malnutrition among elderly in patients with diabetes was observed, regardless of BMI. Malnutrition, albumin, and MNA score were related to LOS, mortality and home discharge.
老年糖尿病患者的营养不良患病率尚不清楚。我们的目标是确定老年糖尿病患者的营养不良患病率,并描述其对预后的影响。
在35家西班牙医院进行了一项观察性多中心研究。使用微型营养评定法(MNA)工具评估营养不良情况。对患者进行随访直至出院。
共纳入1090名受试者(年龄78±7.1岁;50%为男性)。39.1%存在营养不良风险,21.2%患有营养不良。15.5%的营养不良受试者和31.9%有风险者的体重指数(BMI)≥30kg/m²。多因素分析显示,女性(比值比[OR]=1.38;95%置信区间[CI]:1.19-1.11)、年龄(OR=1.04;95%CI:1.02-1.06)和糖尿病并发症的存在(OR=1.97;95%CI:1.52-2.56)与营养不良相关。有风险和营养不良患者的住院时间(LOS)比营养良好的患者更长(分别为12.7±9.9天和15.7±12.8天,对比10.7±9.9天;p<0.0001)。在按年龄和性别进行调整后,MNA评分(OR=0.895;95%CI:0.814-0.985)和白蛋白(OR=0.441;95%CI:0.212-0.915)与死亡率相关。MNA评分与出院回家的可能性相关(OR=1.150;95%CI:1.084-1.219)。
观察到老年糖尿病患者中营养不良的患病率很高,与BMI无关。营养不良、白蛋白和MNA评分与住院时间、死亡率和出院回家情况相关。