Department of Neurosurgery, Nahraine Medical College, Baghdad, Iraq.
World Neurosurg. 2013 Nov;80(5):620-6. doi: 10.1016/j.wneu.2013.06.013. Epub 2013 Jul 9.
Vertebral hydatid cysts are found in <1% of all cases of hydatidosis. The pathology has an infiltrative malignant nature, affecting the vertebral body with possible extension in the epidural space. This pathomechnism is associated with a high rate of morbidity, mortality, and relapse. Decompressive surgery combined with antihelminthic therapy is recommended to eradicate the disease and prevent recurrence.
Between 1990 and 2007, 36 patients with a mean age of 31 years were diagnosed as having spinal hydatid disease and underwent surgery on several occasions for multiple recurrences. Combined chemotherapy with albendazole also was given.
Initial surgery and chemotherapy steadied clinical progression and functional deterioration, but with a recurrence rate of 89% and an average time to disease recurrence of 2.5 years, did not improve the known malignant course of disease in comparison to the literature.
The devastating and malignant course of this disease, which affects mostly young patients, demands continuous development of preventive care in endemic regions, the early detection and screening of the diseased patients, and eventually the advancement of the combined medical and surgical treatment.
在所有包虫病病例中，脊椎包虫囊肿仅占<1%。该病理学具有浸润性恶性特征，累及椎体并可能向硬膜外间隙扩展。这种发病机制与高发病率、死亡率和复发率相关。推荐减压手术联合抗寄生虫治疗以根除疾病并预防复发。
1990 年至 2007 年间，36 名平均年龄为 31 岁的患者被诊断为患有脊髓包虫病，并因多次复发而接受多次手术。同时给予阿苯达唑联合化疗。
初次手术和化疗稳定了临床进展和功能恶化，但复发率为 89%，平均复发时间为 2.5 年，与文献报道相比，并未改善已知的疾病恶性进程。
这种疾病对大多数年轻患者具有破坏性和恶性，需要在流行地区不断开展预防保健工作，早期发现和筛查患病患者，并最终推进联合医学和手术治疗。
