Department of Physical Therapy, Maastricht University Medical Centre (MUMC), Maastricht, The Netherlands.
Curr Opin Pulm Med. 2013 Sep;19(5):524-30. doi: 10.1097/MCP.0b013e328363f563.
This review focuses on innovations in the field of assessment and treatment of muscle weakness and exercise intolerance in sarcoidosis and the association between these and fatigue, dyspnea and quality of life (QoL).
Muscle strength and exercise intolerance are prevalent in patients with sarcoidosis. Exercise testing can be used to identify the presence of strength deficits and exercise intolerance. Routinely performed clinical tests, including lung function tests and imaging methods, are only weakly related to these nonspecific health complaints. Assessment of exercise capacity might also be useful for the early detection of parenchymal involvement and diagnosis of sarcoidosis-associated pulmonary hypertension. Both muscle weakness and exercise intolerance have been suggested as underlying causes of fatigue and dyspnea complaints, resulting in reduced QoL. Research is required to find out whether a multidisciplinary rehabilitation program is of clinical benefit in the management of sarcoidosis patients.
This review underlines the added value of physical testing in the management of sarcoidosis patients, especially in those with unexplained physical complaints.
本文重点介绍了结节病肌肉无力和运动不耐受评估和治疗领域的创新，以及这些与疲劳、呼吸困难和生活质量（QoL）之间的关联。
结节病患者普遍存在肌肉无力和运动不耐受。运动试验可用于确定是否存在肌力缺陷和运动不耐受。常规进行的临床检查，包括肺功能检查和影像学方法，与这些非特异性健康主诉的相关性很弱。评估运动能力也可能有助于早期发现实质受累和诊断结节病相关肺动脉高压。肌肉无力和运动不耐受都被认为是疲劳和呼吸困难的潜在原因，导致生活质量下降。需要研究多学科康复计划是否对结节病患者的管理具有临床益处。
本综述强调了身体测试在结节病患者管理中的附加价值，尤其是对那些有不明原因的身体主诉的患者。
