功能化氮化硼纳米管介孔硅用于化疗药物的细胞内递送。
Boron nitride nanotubes functionalized with mesoporous silica for intracellular delivery of chemotherapy drugs.
机构信息
World Premier International Center for Materials Nanoarchitectonics (WPI-MANA), National Institute for Materials Science (NIMS), Namiki 1-1, Tsukuba, Ibaraki 305-0044, Japan.
出版信息
Chem Commun (Camb). 2013 Aug 25;49(66):7337-9. doi: 10.1039/c3cc42743a.
PMID:23851619
Abstract
Boron nitride nanotube (BNNT)@mesoporous silica hybrids with controllable surface zeta potential were fabricated for intracellular delivery of doxorubicin. The materials showed higher suspension ability, doxorubicin intracellular endocytosis efficiency, and LNcap prostate cancer cell killing ability compared with naked BNNTs.
摘要
氮化硼纳米管（BNNT）@介孔硅杂化物具有可控的表面 zeta 电位，可用于阿霉素的细胞内递送。与裸露的 BNNTs 相比，该材料具有更高的悬浮能力、阿霉素的细胞内内吞效率和 LNcap 前列腺癌细胞杀伤能力。
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