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儿童 3-T MRI 检查中偶然发现的松果体囊肿。

Incidental pineal cysts in children who undergo 3-T MRI.

机构信息

Department of Radiology, University of Tennessee Health Science Center, Memphis, TN, USA,

出版信息

Pediatr Radiol. 2013 Dec;43(12):1577-83. doi: 10.1007/s00247-013-2742-x. Epub 2013 Jul 14.

DOI:10.1007/s00247-013-2742-x
PMID:23852563
Abstract

BACKGROUND

Pineal cysts, both simple and complex, are commonly encountered in children. More cysts are being detected with MR technology; however, nearly all pineal cysts are benign and require no follow-up.

OBJECTIVE

To discover the prevalence of pineal cysts in children at our institution who have undergone high-resolution 3-T MRI.

MATERIALS AND METHODS

We retrospectively reviewed 100 consecutive 3-T brain MRIs in children ages 1 month to 17 years (mean 6.8 ± 5.1 years). We evaluated 3-D volumetric T1-W imaging, axial T2-W imaging, axial T2-W FLAIR (fluid attenuated inversion recovery) and coronal STIR (short tau inversion recovery) sequences. Pineal parenchymal and cyst volumes were measured in three planes. Cysts were analyzed for the presence and degree of complexity.

RESULTS

Pineal cysts were present in 57% of children, with a mean maximum linear dimension of 4.2 mm (range 1.5-16 mm). Of these cysts, 24.6% showed thin septations or fluid levels reflecting complexity. None of the cysts demonstrated complete T2/FLAIR signal suppression. No cyst wall thickening or nodularity was present. There was no significant difference between the ages of children with and without cysts. Cysts were more commonly encountered in girls than boys (67% vs. 52%; P = 0.043). There was a slight trend toward increasing pineal gland volume with age.

CONCLUSION

Pineal cysts are often present in children and can be incidentally detected by 3-T MRI. Characteristic-appearing pineal cysts in children are benign, incidental findings, for which follow-up is not required if there are no referable symptoms or excessive size.

摘要

背景

松果体囊肿,无论是单纯性还是复杂性,在儿童中都很常见。随着磁共振技术的发展,更多的囊肿被检测到;然而,几乎所有的松果体囊肿都是良性的,不需要随访。

目的

发现我们机构在接受高分辨率 3-T MRI 检查的儿童中松果体囊肿的患病率。

材料与方法

我们回顾性分析了 100 例连续的 3-T 脑部 MRI 检查,受检者年龄为 1 个月至 17 岁(平均 6.8 ± 5.1 岁)。我们评估了 3-D 容积 T1-W 成像、轴位 T2-W 成像、轴位 T2-W FLAIR(液体衰减反转恢复)和冠状位 STIR(短 tau 反转恢复)序列。在三个平面测量松果体实质和囊肿体积。分析囊肿的存在和复杂性程度。

结果

松果体囊肿在 57%的儿童中存在,最大线性直径的平均值为 4.2mm(范围 1.5-16mm)。这些囊肿中,24.6%显示薄分隔或反映复杂性的液平。没有囊肿表现出完全的 T2/FLAIR 信号抑制。没有囊肿壁增厚或结节。有囊肿和无囊肿的儿童年龄之间无显著差异。囊肿在女孩中比男孩中更常见(67%比 52%;P=0.043)。松果体体积随年龄略有增加的趋势。

结论

松果体囊肿在儿童中很常见,3-T MRI 可以偶然发现。在没有可归因症状或过大体积的情况下,具有特征性表现的儿童松果体囊肿是良性的偶然发现,不需要随访。

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Pineal cysts in children.儿童松果体囊肿
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Clin Neuroradiol. 2012 Mar;22(1):69-77. doi: 10.1007/s00062-011-0110-5. Epub 2011 Nov 20.
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Prevalence and natural history of pineal cysts in adults.松果体囊肿在成人中的患病率和自然史。
小儿松果体区囊肿:谜还是神经液系统障碍?
Childs Nerv Syst. 2023 Dec;39(12):3457-3466. doi: 10.1007/s00381-023-06000-4. Epub 2023 Jun 1.
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Case report: Fluctuating tumor markers in a boy with gonadotropin-releasing hormone-independent precocious puberty induced by a pineal germ cell tumor.病例报告:松果体生殖细胞瘤诱发的促性腺激素释放激素非依赖性性早熟男孩体内肿瘤标志物的波动情况
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Is there any relationship between autism and pineal gland volume?自闭症与松果体体积之间存在关联吗?
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Prevalence and Risk Factors of Incidental Findings in Brain MRIs of Healthy Neonates-The FinnBrain Birth Cohort Study.健康新生儿脑部磁共振成像中偶然发现的患病率及危险因素——芬兰脑出生队列研究
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Gland Surg. 2019 Apr;8(2):133-140. doi: 10.21037/gs.2019.01.02.
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Neuroradiology. 2017 Dec;59(12):1265-1273. doi: 10.1007/s00234-017-1926-8. Epub 2017 Sep 23.
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The natural history of pineal cysts in children and young adults.儿童及青年松果体囊肿的自然病史。
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