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儿童松果体囊肿

Pineal cysts in children.

作者信息

Lacroix-Boudhrioua V, Linglart A, Ancel P Y, Falip C, Bougnères P F, Adamsbaum C

出版信息

Insights Imaging. 2011 Dec;2(6):671-678. doi: 10.1007/s13244-011-0117-0. Epub 2011 Aug 10.

DOI:10.1007/s13244-011-0117-0
PMID:22347985
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3259367/
Abstract

OBJECTIVE

To describe the prevalence and characteristics of pineal cysts found on MRI in children. METHODS: This is a retrospective monocentric study of all brain magnetic resonance imaging (MRI) examinations performed under the same technical conditions for checking the idiopathic nature of short stature (ISS group, n = 116) and for the investigation of central precocious puberty (CPP) over a 3-year period (n = 56). Dimensions, wall and septal thickness, number of locules, signal intensity, and the presence of a solid component were analysed. Ten of 19 cysts were re-evaluated (follow-up interval 4-28 months). The prevalence of the pineal cysts was compared between the two groups using χ2 and Fisher's exact tests, and a significance threshold of p < 0.05. RESULTS: The prevalence of cysts was comparable in the two groups, CPP (10.7%) and ISS (11.2%). Cyst characteristics were similar in the two groups and 74% had thin septations. None of the cysts changed on follow-up. None of the children with pineal cysts exhibited neurological signs. CONCLUSION: Benign pineal cysts are a common finding in young children. High-resolution MRI demonstrates that these cysts are often septated. This pattern is a normal variant and does not require follow-up MR imaging or IV contrast media.

摘要

目的

描述儿童磁共振成像(MRI)检查中发现的松果体囊肿的患病率及特征。方法:这是一项回顾性单中心研究,纳入了在相同技术条件下进行的所有脑磁共振成像(MRI)检查,这些检查是在3年期间内用于检查特发性矮小症(ISS组,n = 116)的特发性性质以及用于中枢性性早熟(CPP)的调查(n = 56)。分析囊肿的大小、壁和间隔厚度、房腔数量、信号强度以及实性成分的存在情况。对19个囊肿中的10个进行了重新评估(随访间隔4 - 28个月)。使用χ2检验和Fisher精确检验比较两组松果体囊肿的患病率,显著性阈值为p < 0.05。结果:两组囊肿的患病率相当,CPP组为10.7%,ISS组为11.2%。两组囊肿特征相似,74%有薄分隔。随访期间囊肿无变化。患有松果体囊肿的儿童均未出现神经学体征。结论:良性松果体囊肿在幼儿中是常见发现。高分辨率MRI显示这些囊肿常为分隔状。这种表现是一种正常变异,无需进行随访MRI检查或静脉注射造影剂。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d31/3289030/e9a475e27f43/13244_2011_117_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d31/3289030/c78f40615f9b/13244_2011_117_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d31/3289030/ed2b40474baa/13244_2011_117_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d31/3289030/89aff6d65340/13244_2011_117_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d31/3289030/74e840568d16/13244_2011_117_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d31/3289030/e9a475e27f43/13244_2011_117_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d31/3289030/c78f40615f9b/13244_2011_117_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d31/3289030/ed2b40474baa/13244_2011_117_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d31/3289030/89aff6d65340/13244_2011_117_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d31/3289030/74e840568d16/13244_2011_117_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d31/3289030/e9a475e27f43/13244_2011_117_Fig5_HTML.jpg

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The natural history of pineal cysts in children and young adults.儿童及青年松果体囊肿的自然病史。
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Prevalence of pineal cysts in children and young adults. Clinical article.儿童及青年松果体囊肿的患病率。临床文章。
J Neurosurg Pediatr. 2009 Sep;4(3):230-6. doi: 10.3171/2009.4.PEDS0951.
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Serial follow-up MRI of indeterminate cystic lesions of the pineal region: experience at a rural tertiary care referral center.松果体区不确定囊性病变的系列随访磁共振成像:一家农村三级医疗转诊中心的经验
松果体囊肿可能促进中枢性性早熟女童的青春期发育:来自中国的单中心研究。
Front Endocrinol (Lausanne). 2024 Feb 8;15:1323947. doi: 10.3389/fendo.2024.1323947. eCollection 2024.
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Central Precocious Puberty in Italian Boys: Data From a Large Nationwide Cohort.意大利男孩的中枢性性早熟:一项大型全国队列研究的数据。
J Clin Endocrinol Metab. 2024 Jul 12;109(8):2061-2070. doi: 10.1210/clinem/dgae035.
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Central precocious puberty secondary to peripheral precocious puberty due to a pineal germ cell tumor: a case and review of literature.松果体生殖细胞瘤导致外周性性早熟继发中枢性性早熟 1 例报告并文献复习
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