IEEE Trans Biomed Circuits Syst. 2010 Feb;4(1):19-26. doi: 10.1109/TBCAS.2009.2035555.
This paper describes experimental results for an application-specific integrated circuit (ASIC), designed for digital heart rate variability (HRV) parameter monitoring and assessment. This ASIC chip measures beat-to-beat (RR) intervals and stores HRV parameters into its internal memory in real time. A wide range of short-term and long-term ECG signals obtained from Physionet was used for testing. The system detects R peaks with millisecond accuracy, and stores up to 2 min of continuous RR interval data and up to 4 min of RR interval histogram. The prototype chip was fabricated in a 0.5 ¿m complementary metal-oxide semiconductor technology on a 3×3 mm(2) die area, with a measured dynamic power consumption of 10 ¿W and measured leakage current of 2.62 nA. The HRV monitoring system including this HRV ASIC, an analog-to-digital converter, and a low complexity microcontroller was estimated to consume 32.5 ¿V, which is seven times lower power than a stand-alone microcontroller performing the same functions. Compact size, low cost, and low power consumption make this chip suitable for a miniaturized portable HRV monitoring system.
本文介绍了一款专用集成电路（ASIC）的实验结果，该集成电路专为数字心率变异性（HRV）参数监测和评估而设计。该 ASIC 芯片实时测量逐拍（RR）间期，并将 HRV 参数存储到内部存储器中。使用来自 Physionet 的广泛的短期和长期 ECG 信号进行了测试。该系统以毫秒级的精度检测 R 波峰值，并存储长达 2 分钟的连续 RR 间期数据和长达 4 分钟的 RR 间隔直方图。该原型芯片采用 0.5 µm 互补金属氧化物半导体技术制造，在 3×3 mm²的芯片面积上，动态功耗为 10 µW，漏电流为 2.62 nA。包括该 HRV ASIC、模数转换器和低复杂度微控制器的 HRV 监测系统估计消耗 32.5 µV，这比执行相同功能的独立微控制器的功耗低 7 倍。该芯片尺寸紧凑、成本低、功耗低，非常适合用于小型化便携式 HRV 监测系统。
