IEEE Trans Biomed Circuits Syst. 2010 Aug;4(4):205-13. doi: 10.1109/TBCAS.2010.2042809.
Low voltage and low power are two key requirements for on-chip realization of wireless power and data telemetry for applications in biomedical sensor instrumentation. Batteryless operation and wireless telemetry facilitate robust, reliable, and longer lifetime of the implant unit. As an ongoing research work, this paper demonstrates a low-power low-voltage sensor readout circuit which could be easily powered up with an inductive link. This paper presents two versions of readout circuits that have been designed and fabricated in bulk complementary metal-oxide semiconductor (CMOS) processes. Either version can detect a sensor current in the range of 0.2 μA to 2 μA and generate square-wave data signal whose frequency is proportional to the sensor current. The first version of the circuit is fabricated in a 0.35-μ m CMOS process and it can generate an amplitude-shift-keying (ASK) signal while consuming 400 μ W of power with a 1.5-V power supply. Measurement results indicate that the ASK chip generates 76 Hz to 500 Hz frequency of a square-wave data signal for the specified sensor current range. The second version of the readout circuit is fabricated in a 0.5-μ m CMOS process and produces a frequency-shift-keying (FSK) signal while consuming 1.675 mW of power with a 2.5-V power supply. The generated data frequency from the FSK chip is 1 kHz and 9 kHz for the lowest and the highest sensor currents, respectively. Measurement results confirm the functionalities of both prototype schemes. The prototype circuit has potential applications in the monitoring of blood glucose level, lactate in the bloodstream, and pH or oxygen in a physiological system/environment.
低电压和低功耗是实现无线电源和数据遥测在生物医学传感器仪器应用中的关键要求。无电池操作和无线遥测可以实现植入单元的稳健、可靠和更长的寿命。作为正在进行的研究工作,本文展示了一种低功耗、低电压的传感器读出电路,可以通过感应链路轻松供电。本文提出了两种已在体硅互补金属氧化物半导体(CMOS)工艺中设计和制造的读出电路版本。这两种版本都可以检测范围在 0.2 μA 到 2 μA 的传感器电流,并生成与传感器电流成正比的方波数据信号。该电路的第一个版本采用 0.35-μm CMOS 工艺制造,可在 1.5 V 电源下消耗 400 μW 的功率生成幅移键控(ASK)信号。测量结果表明,对于指定的传感器电流范围,ASK 芯片产生 76 Hz 至 500 Hz 的方波数据信号频率。读出电路的第二个版本采用 0.5-μm CMOS 工艺制造,在 2.5 V 电源下消耗 1.675 mW 的功率时产生频移键控(FSK)信号。FSK 芯片产生的数据频率分别为最低和最高传感器电流的 1 kHz 和 9 kHz。测量结果证实了两种原型方案的功能。该原型电路在监测血糖水平、血液中的乳酸、生理系统/环境中的 pH 值或氧气方面具有潜在的应用。