Borderon E, Tescher M, Du Rouchet E, Lemaire B, Desroche A, Megier P
Laboratoire de Biologie, CHR d'Orléans.
Pathol Biol (Paris). 1990 Jun;38(5 ( Pt 2)):538-42.
From June 1988 to October 1989, 190 women from the department of Obstetrics-Gynecology with bacteriuria due to Gram-negative rods were studied. One hundred and three were investigated as ambulatory patients. Fifty three had received treatment with a bêta-lactam antibiotic during the past three months and 11 between three and six-months before sampling. The organisms causing bacteriuria were 163 E. coli, 12 P. mirabilis and 15 were due to other species. Thirty three E. coli and the 15 other species were resistant to amoxicillin and/or to cefalotin. When comparing previous treatment and resistance to amino-penicillins it appears that: of the women who had received a beta-lactam antibiotic within the three months before testing, 57% of the strains recovered were found resistant for amino-penicillins; of the women without treatment during the past six months, 89% of the strains recovered were sensitive and six per cent of E. coli plus five per cent of another Gram negative rod were resistant to amino-penicillins.
1988年6月至1989年10月，对妇产科190名因革兰氏阴性杆菌导致菌尿症的女性进行了研究。其中103名作为门诊患者接受调查。53名在过去三个月内接受了β-内酰胺类抗生素治疗，11名在采样前三至六个月接受过治疗。导致菌尿症的病原体为163株大肠杆菌、12株奇异变形杆菌以及15株其他菌种。33株大肠杆菌和15株其他菌种对阿莫西林和/或头孢噻吩耐药。比较既往治疗情况与对氨基青霉素的耐药性时发现：在检测前三个月内接受过β-内酰胺类抗生素治疗的女性中，分离出的菌株有57%对氨基青霉素耐药；在过去六个月内未接受治疗的女性中，分离出的菌株有89%敏感，6%的大肠杆菌和5%的其他革兰氏阴性杆菌对氨基青霉素耐药。
