Joshi S, Hegde A M, Rai K, Shetty S
Department of Pedodontics, Rural Dental College, Loni, Dist. Ahmednagar, Maharashtra, India.
J Clin Pediatr Dent. 2013 Spring;37(3):309-13. doi: 10.17796/jcpd.37.3.7808167071871754.
The aim of present study was to evaluate the salivary sialic acid levels in Acute Lymphoblastic Leukemic (ALL) children and to correlate it with dental caries experience.
A total of 120 children aged 4-10 yrs were divided into 4 groups of 30 each. Dental caries experience was recorded followed by un-stimulated saliva collection.
The mean salivary sialic acid levels of the study group were much higher when compared with the control group, which was statistically significant. A linear relationship between salivary sialic acid levels and dental caries in leukemic children was observed.
The findings of our study conclude that salivary sialic acid levels may have a potent activity in dental caries process and can be used as a useful marker in cancer
本研究旨在评估急性淋巴细胞白血病（ALL）患儿唾液中唾液酸水平，并将其与龋齿经历相关联。
总共120名4至10岁的儿童被分为4组，每组30人。记录龋齿经历，随后收集非刺激性唾液。
与对照组相比，研究组的平均唾液唾液酸水平要高得多，具有统计学意义。观察到白血病患儿唾液唾液酸水平与龋齿之间存在线性关系。
我们的研究结果表明，唾液唾液酸水平可能在龋齿过程中具有重要作用，并且可作为癌症的有用标志物。
