Gonçalves Cíntia Ferreira, E Silva Mariana Vargas Lindemaier, Costa Luciane Rezende, de Toledo Orlando Ayrton
Health Sciences Graduate Program, University of Brasília, Brasília, Federal District, Brazil.
, Avenida Teotônio Segurado, Cj. 01, Lt. 01, Sl. 508, Plano Diretor Sul, Palmas, TO, CEP: 77061-002, Brazil.
BMC Oral Health. 2015 Oct 16;15(1):127. doi: 10.1186/s12903-015-0110-y.
The oral condition in children undergoing oncohematological treatment can have a negative impact on the course of disease. Little is known about survival of tooth restorations in these patients. The aim of this study was to evaluate the longevity of restorations and sealants performed by Atraumatic Restoration Treatment (ART) in patients undergoing oncohematological treatment.
ART single surface restorations and sealants were performed in the experimental group (E), which comprised children (2-13 years old) undergoing oncohematological treatment, and in the control group (C), in which patients did not undergo such treatment. The same examiner evaluated the ART at 1, 3, 6 and 12 months after preparation, using the same criteria for restorations and sealants. ART was successful if the sealant or restoration did not need a repair in the follow-up assessment. Descriptive, bivariate and Cox's proportional hazard analyses were performed at a significance level of 5 %.
The two groups, one including 24 children (E) and the other 14 children (C), received 101 and 52 ART procedures, respectively. The success rates were 95.0 % (E) and 100 % (C) at 1 month (P = 0.233); 81.2 % (E) and 92.3 % (C) at 3 months (P = 0.009); 72.2 % (E) and 80.8 % (C) at 6 months (P = 0.050) and 48.5 % (E) and 73.1 % (C) at 12 months (P = 0.001). The final Cox's regression model for occurrence of ART failure needing repair did not show differences between groups (E: OR = 1.6, 95 % CI 0.8-2.9); primary teeth had a shorter survival than permanent teeth (OR = 2.1, 95 % CI 1.2-3.7).
Oncohematological treatment did not interfere with the longevity of ART restorations and sealants, which suggests the potential use of this technique in children undergoing chemotherapy.
Brazilian Clinical Trials Registry (REBEC) RBR-2c3c52. Registered 5 June 2014. http://www.ensaiosclinicos.gov.br/rg/RBR-2c3c52/.
接受肿瘤血液学治疗的儿童口腔状况可能对疾病进程产生负面影响。对于这些患者牙齿修复体的存留情况知之甚少。本研究的目的是评估在接受肿瘤血液学治疗的患者中，非创伤性修复治疗（ART）所进行的修复体和窝沟封闭剂的使用寿命。
在实验组（E组）对接受肿瘤血液学治疗的儿童（2至13岁）以及对照组（C组）未接受此类治疗的患者进行ART单面修复和窝沟封闭。同一位检查者在制备后1、3、6和12个月使用相同的修复体和窝沟封闭剂标准对ART进行评估。如果在随访评估中窝沟封闭剂或修复体不需要修复，则ART为成功。在5%的显著性水平上进行描述性、双变量和Cox比例风险分析。
两组，一组包括24名儿童（E组），另一组包括14名儿童（C组），分别接受了101次和52次ART操作。1个月时成功率分别为95.0%（E组）和100%（C组）（P = 0.233）；3个月时为81.2%（E组）和92.3%（C组）（P = 0.009）；6个月时为72.2%（E组）和80.8%（C组）（P = 0.
