Teke Mehmet Y, Elgin Ufuk, Sen Emine, Ozdal Pinar, Ozturk Faruk
Ulucanlar Eye Research Hospital, Ulucanlar Caddesi, No: 59, PK06420, Altindag, Ankara, Turkey.
Int Ophthalmol. 2014 Jun;34(3):457-63. doi: 10.1007/s10792-013-9830-7. Epub 2013 Jul 16.
Our aim was to detect the early effects of pars plana vitrectomy (PPV) combined with intravitreal silicone oil (SO) on corneal biomechanics. 19 eyes underwent PPV with SO tamponade (group 1) and 16 eyes underwent. PPV without tamponade (group 2). Corneal biomechanical parameters were measured preoperatively and at the first postoperative month by ocular response analyzer. The mean preoperative intraocular pressure (IOP) by Goldmann applanation tonometry (GAT) and the mean corneal-compensated intraocular pressure (IOPcc) were significantly lower in group 1 than group 2 (p = 0.005, p = 0.002, respectively). The mean preoperative corneal hysteresis (CH) and corneal resistance factor (CRF) were significantly higher in group 1 than group 2 (p = 0.017, p = 0.002, respectively). However, the difference in Goldmann-correlated intraocular pressure (IOPg) between the groups was not significant (p = 0.360). In group 1, IOPcc, IOPg and IOP-GAT significantly increased postoperatively (p = 0.002, p = 0.004, p = 0.002, respectively) but CH and CRF decreased (p = 0.007, p = 0.153, respectively). In group 2, IOPcc, IOPg and IOP (GAT) increased postoperatively but the differences were not significant (p = 0.851, p = 0.693, p = 0.336, respectively). The mean CRF increased significantly (p = 0.026) postoperatively but the decrease in CH was not significant (p = 0.196). Statistically significant differences were found in the changes of preoperative and postoperative means of IOPcc, IOPg, IOP-GAT and CRF between the groups (p = 0.024, p = 0.037, p = 0.014, p = 0.006, respectively). However, the difference in the decreases in CH between the two groups was not statistically significant (p = 0.206). SO tamponade may affect corneal biomechanical parameters in the early postoperative period, which may be related to the surgery itself, SO tamponade or IOP changes.
我们的目的是检测玻璃体切除术（PPV）联合玻璃体内硅油（SO）对角膜生物力学的早期影响。19只眼接受了PPV联合SO填塞（第1组），16只眼接受了未进行填塞的PPV（第2组）。术前及术后第1个月通过眼反应分析仪测量角膜生物力学参数。第1组采用Goldmann压平眼压计（GAT）测量的术前平均眼压（IOP）及平均角膜补偿眼压（IOPcc）显著低于第2组（分别为p = 0.005，p = 0.002）。第1组术前平均角膜滞后（CH）和角膜阻力因子（CRF）显著高于第2组（分别为p = 0.017，p = 0.002）。然而，两组间Goldmann相关眼压（IOPg）的差异不显著（p = 0.360）。在第1组中，术后IOPcc、IOPg和IOP - GAT显著升高（分别为p = 0.002，p = 0.004，p = 0.002），但CH和CRF降低（分别为p = 0.007，p = 0.153）。在第2组中，术后IOPcc、IOPg和IOP（GAT）升高，但差异不显著（分别为p = 0.851，p = 0.693，p = 0.336）。术后平均CRF显著升高（p = 0.026），但CH的降低不显著（p = 0.196）。两组间术前及术后IOPcc、IOPg、IOP - GAT和CRF平均值变化存在统计学显著差异（分别为p = 0.024，p = 0.037，p = 0.014，p = 0.006）。然而，两组间CH降低的差异无统计学意义（p = 0.206）。SO填塞可能在术后早期影响角膜生物力学参数，这可能与手术本身、SO填塞或眼压变化有关。
