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甲状腺全切除术后10年复发为鳞状细胞癌的乳头状甲状腺癌:快速进展性乳头状甲状腺癌的经验教训

Papillary thyroid carcinoma recurring as squamous cell carcinoma 10 years after total thyroidectomy: lessons from rapidly progressive papillary thyroid carcinoma.

作者信息

Lee Ji In, Chung Yun Jae, Lee Sei Young

机构信息

Department of Internal Medicine, Chung-Ang University Hospital, Chung-Ang University College of Medicine, Korea.

出版信息

Intern Med. 2013;52(14):1593-7. doi: 10.2169/internalmedicine.52.9310. Epub 2013 Jul 15.

Abstract

Primary squamous cell carcinoma (SCC) of the thyroid is very rare. There are no reports of metastatic papillary thyroid carcinoma (PTC) converting to SCC in cervical lymph nodes following total thyroidectomy due to conventional PTC. An 86-year-old woman with a remote history of total thyroidectomy due to PTC underwent palliative neck surgery to treat recurrent bleeding originating from a metastatic tumor of the cervical lymph nodes. The resected mass was composed of mixed SCC and PTC. Although primary SCC rarely occurs in the thyroid, conversion of PTC to SCC should be suspected if preexisting PTC exhibits highly aggressive behavior.

摘要

甲状腺原发性鳞状细胞癌(SCC)非常罕见。尚无因传统乳头状甲状腺癌(PTC)行全甲状腺切除术后,颈部淋巴结转移性PTC转化为SCC的报道。一名86岁女性,既往因PTC行全甲状腺切除术,现因颈部淋巴结转移瘤复发出血接受姑息性颈部手术。切除的肿物由SCC和PTC混合组成。虽然原发性SCC很少发生于甲状腺,但如果既往存在的PTC表现出高度侵袭性行为,则应怀疑PTC转化为SCC。

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