Jawed Shireen, Ejaz Saima, Rehman Rehana
Department of Physiology, Dow International Medical College, Karachi.
J Pak Med Assoc. 2012 Aug;62(8):772-5.
To determine the effect of smoking on forced vital capacity, forced expiratory volume in 1 sec. and the ratio between the two.
The cross-sectional study was conducted in two Karachi-based medical colleges, Dow International Medical College and Bahria University Medical and Dental College between March 2010 and February 2011. The study comprised 244 male students (aged 19-25 years) who were selected by simple random sampling. A detailed questionnaire was got filled up by each participant to assess the smoking status and respiratory disease symptoms. Spirometry was performed by power lab spirometer according to the recommended guidelines of the American Thoracic Society and the European Respiratory Society by highly trained power lab instructor. Data was analysed using SPSS version 16. Means and standard deviations were worked out for continuous variables, while analyses of variance was done to see the difference among various categories.
A statistically significant difference was found in the mean spirometric values of forced expiratory volume, forced expiratory capacity and their ratio between the smokers and the non-smokers. The first two factors were significantly lower among those who smoked > 10-20 cigarettes/day. But there was no statistically significant difference in the mean ratio of passive smokers and former smokers.
The deterioration of lung functions and habitual cough is directly related to the number of cigarettes smoked per day in young smokers.
确定吸烟对用力肺活量、1秒用力呼气量以及两者之间比值的影响。
这项横断面研究于2010年3月至2011年2月在卡拉奇的两所医学院——道国际医学院和巴哈里亚大学医学院及牙科学院进行。该研究包括244名男性学生(年龄在19 - 25岁之间),通过简单随机抽样选取。每位参与者填写一份详细问卷,以评估吸烟状况和呼吸道疾病症状。由训练有素的力量实验室教员按照美国胸科学会和欧洲呼吸学会的推荐指南,使用力量实验室肺活量计进行肺活量测定。使用SPSS 16版软件分析数据。计算连续变量的均值和标准差,同时进行方差分析以查看不同类别之间的差异。
吸烟者与非吸烟者在用力呼气量、用力呼气容量及其比值的平均肺活量测定值方面存在统计学显著差异。在每天吸烟超过10 - 20支的人群中,前两个因素显著更低。但被动吸烟者和既往吸烟者的平均比值没有统计学显著差异。
年轻吸烟者的肺功能恶化和习惯性咳嗽与每日吸烟量直接相关。