Hou Wenlu, Yiin Raphael Shih Zhu, Goh Chin Kong
Department of Radiology, Changi General Hospital, Singapore.
J Radiol Case Rep. 2019 Sep 30;13(9):1-7. doi: 10.3941/jrcr.v13i9.3739. eCollection 2019 Sep.
Metronidazole induced encephalopathy is a rare central nervous system toxicity, which may be completely reversible with prompt cessation of metronidazole usage. We present a case of metronidazole induced encephalopathy in a 59-year-old man with a history of Whipple's procedure for pancreatic neuroendocrine tumour. The characteristic magnetic resonance imaging features of metronidazole induced encephalopathy and its main differential diagnosis, Wernicke's encephalopathy, are discussed.
甲硝唑诱发的脑病是一种罕见的中枢神经系统毒性反应，及时停用甲硝唑后可能完全可逆。我们报告一例59岁男性因胰腺神经内分泌肿瘤接受惠普尔手术，发生了甲硝唑诱发的脑病。文中讨论了甲硝唑诱发脑病的特征性磁共振成像表现及其主要鉴别诊断——韦尼克脑病。
