Biozentrum, University of Basel, Klingelbergstrasse 70, CH-4056, Basel, Switzerland.
Biochem Soc Trans. 2013 Aug;41(4):887-8. doi: 10.1042/BST20130092.
In the present article, I discuss recent developments in the naming of the TOR (target of rapamycin) protein. In particular, I address the issue of mammalian target of rapamycin (mTOR) versus the newer mechanistic target of rapamycin (MTOR). mTOR is the name given by the TOR community almost two decades ago and widely used ever since. MTOR is a name recently imposed on the TOR community by database curators and used mainly by newcomers. I argue that MTOR is causing needless confusion in the field, and conclude that one should use the name mTOR.
在本文中,我讨论了雷帕霉素靶蛋白(TOR)命名的最新进展。特别是,我探讨了哺乳动物雷帕霉素靶蛋白(mTOR)与新型雷帕霉素靶蛋白(MTOR)的问题。mTOR 是 TOR 研究社区在近 20 年前命名的,并且自那时以来一直广泛使用。MTOR 是数据库管理员最近强加给 TOR 研究社区的名称,主要被新进入该领域的人使用。我认为 MTOR 给该领域造成了不必要的混淆,并得出结论,应该使用 mTOR 这个名称。