Shimada Ayako, Nakamura Takeshi, Ishii Masatsugu, Chiba Naokazu, Ishikawa Shuji, Arisawa Yoshito, Hashimoto Mitsumasa
Dept. of Surgery, Kawasaki Municipal Ida Hospital, Japan.
Gan To Kagaku Ryoho. 2013 May;40(5):663-5.
A fifty-two-year-old female with advanced rectal cancer underwent low anterior resection and hysterectomy. After local pelvic recurrence, she underwent radiation therapy(50 Gy in total), and then chemotherapy(XELOX+bevacizumab)was started. However, left femoral pain developed after the second course of chemotherapy, and necrotizing fasciitis associated with lower bowel perforation was found. Although bowel perforation is known as a serious side-effect of bevacizumab, its association with fasciitis is rare.
