McLain B I, Davidson P M, Stokes K B, Beasley S W
Department of Gastroenterology, Royal Children's Hospital, Melbourne.
Arch Dis Child. 1990 Jul;65(7):760-2. doi: 10.1136/adc.65.7.760.
Seventeen children underwent 19 bowel resections as part of their management of Crohn's disease. Thirteen children had evidence of retardation of linear growth preoperatively, of whom 12 exhibited catch up growth, crossing at least one centile band, after resection. Seven of the 12 showed early signs of puberty at the time of resection and one child was regarded as being fully pubertal. All children were symptomatic before their surgery; at one year 11 were asymptomatic and three others were substantially improved. Surgical resection of localised Crohn's disease, followed by adequate nutritional support has lead to catch up growth and a prolonged symptom free period in most of our patients and this was not limited by their age or stage of puberty.
17名儿童接受了19次肠道切除术，作为其克罗恩病治疗的一部分。13名儿童术前有线性生长迟缓的证据，其中12名在切除术后出现追赶生长，至少跨越一条百分位带。12名中的7名在切除时出现青春期早期迹象，1名儿童被认为已完全进入青春期。所有儿童在手术前均有症状；1年后，11名无症状，另外3名有明显改善。局限性克罗恩病的手术切除，再加上充足的营养支持，已使我们的大多数患者实现了追赶生长，并延长了无症状期，这不受他们的年龄或青春期阶段限制。
